Haku
Viitteet 1-9 / 9
Characterization of in vitro outer blood retinal barrier model
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: The human eye has anatomically closed structure, due to the blood retinal barrier (BRB) which is protecting the photoreceptor cells. It comprises of three layers: retinal pigment epithelial cells ...
Characterization of the protease phenotype of cultured human mast cells during their differentiation and maturation
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
ABSTRACT
Background and Aims: Mast cells (MCs) are tissue-dwelling effector cells of innate and adaptive immunity that differentiate in peripheral tissues from committed circulating progenitor cells of bone marrow origin. ...
Culturing human embryonic stem cell -derived neural cells in microfluidic polydimethylsiloxane structures
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Capture of hydrocortisone binding avidins from a combinatorial library based on chicken avidin scaffold
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Functional effects of SKIL overexpression in prostate cancer cell lines
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Prostate cancer is among the most common malignancies in the world affecting millions of men worldwide. Molecular mechanisms behind the prostate cancer are still poorly understood. Genomic copy-number ...
The application of qPCR for characterization of LQTS-specific cardiomyocytes derived from induced pluripotent stem cells
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Long QT syndrome (LQTS) is an inherent cardiac disorder causing severe arrhythmias due to mutations in cardiac ion channel genes. Four founder mutations causing LQTS have been identified from Finland ...
BMP4-induced microRNAs in breast cancer cell lines
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Breast cancer is the leading cause of mortality in women worldwide. In cancer, deregulation of signaling pathways, such as of the growth factor BMP4, is a common phenomenon. BMP4 is known to have a ...
UNC13B - A potential target gene of 9p13.3 amplicon in prostate cancer
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Backround and aims: Prostate cancer is the most common cancer in men in Western countries. It is a highly heterogeneous disease both clinically and genetically. Multiple genomic rearrangements are associated with the ...