Haku
Viitteet 111-120 / 133
Effects of exonuclease deficiency on the biochemical properties of the human mitochondrial replicase
(2013)
Pro gradu -tutkielma
Pro gradu -tutkielma
Functional effects of SKIL overexpression in prostate cancer cell lines
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Prostate cancer is among the most common malignancies in the world affecting millions of men worldwide. Molecular mechanisms behind the prostate cancer are still poorly understood. Genomic copy-number ...
The application of qPCR for characterization of LQTS-specific cardiomyocytes derived from induced pluripotent stem cells
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Long QT syndrome (LQTS) is an inherent cardiac disorder causing severe arrhythmias due to mutations in cardiac ion channel genes. Four founder mutations causing LQTS have been identified from Finland ...
Zebrafish model for mycobacterial infection
(2011)
Pro gradu -tutkielma
Pro gradu -tutkielma
M. marinum infection in the zebrafish (Danio rerio) is a well-established model of human tuberculosis. In this project, methodology for experimental infections and assessment of the disease progression was set up and ...
BMP4-induced microRNAs in breast cancer cell lines
(2015)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Breast cancer is the leading cause of mortality in women worldwide. In cancer, deregulation of signaling pathways, such as of the growth factor BMP4, is a common phenomenon. BMP4 is known to have a ...
Brave New Avidins
(2011)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: The extremely high affinity of (strep)avidin towards biotin (Kd≈10-15-10-16) and stability enables its use in a variety of applications; for example, in targeted drug therapy, affinity chromatography ...
Sequence elements regulating alphavirus RNA replication
(2011)
Pro gradu -tutkielma
Pro gradu -tutkielma
Bioaktiivisten tripeptidien (IPP ja VPP) vaikutus ihmisen verisuonitonusta sääteleviin entsyymeihin ACE1, eNOS ja COX-2 napanuoran laskimon endoteelisoluissa (HUVEC)
(2011)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tausta ja tavoitteet: Kohonnut verenpaine on vakava terveysongelma, johon nykytiedon mukaan voidaan vaikuttaa bioaktiivisia tripeptidejä (IPP ja VPP) sisältävällä ruokavaliolla. Vaikutusmekanismi on toistaiseksi puutteellisesti ...
Setting up Methods for the Study of Intracellular Mechanotransduction
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Fokaaliadheesiot (FA) ovat suuria proteiinikomplekseja, joiden avulla solut tarttuvat ympäristönsä solunulkoiseen matriksiin liittämällä sen mekaanisesti solunsisäiseen tukirankaansa. FA:t ovat mekanosensorisia rakenteita, ...
Fluorescent labeling of human embryonic stem cell -derived neurons and characterization of their network connection development
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Cell transplantation therapy is an alternative treatment for defects in tissues with poor regeneration and lack of efficient treatments. One of such tissues is the central nervous system tissue. However, cell transplantation ...