Trepo - Selaus tekijän mukaan "Hakama, Matti"
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Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials
Early Breast Cancer Trialists' Collaborative Group (EBCTCG); Coleman, R; Powles, T; Hakama, Matti et al. (2015)
articleBACKGROUND: Bisphosphonates have profound effects on bone physiology, and could modify the process of metastasis. We undertook collaborative meta-analyses to clarify the risks and benefits of adjuvant bisphosphonate ... -
Alternative technologies in cervical cancer screening: a randomised evaluation trial
Anttila, Ahti; Hakama, Matti; Kotaniemi-Talonen, Laura; Nieminen, Pekka (2006)
articleBackground Cervical cancer screening programmes have markedly reduced the incidence and mortality rates of the disease. A substantial amount of deaths from the disease could be prevented further by organised screening ... -
Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials
Early Breast Cancer Trialists' Collaborative Group (EBCTCG); Dowsett, M; Forbes, JF; Hakama, Matti et al. (2015)
articleBACKGROUND: The optimal ways of using aromatase inhibitors or tamoxifen as endocrine treatment for early breast cancer remains uncertain. METHODS: We undertook meta-analyses of individual data on 31,920 postmenopausal ... -
Challenges in evaluation of screening for gastric cancer among men based on nonrandomized design
Vohlonen, Ilkka; Härkönen, Matti; Malila, Nea; Sipponen, Pentti; Koistinen, Veli; Hakama, Matti (2017)
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Effect of characteristics of women on attendance in blind and non-blind randomised trials: analysis of recruitment data from the EPHT Trial
Veerus, Piret; Fisher, Krista; Hemminki, Elina; Hovi, Sirpa-Liisa; Hakama, Matti (2016)
articleTo analyse the effect of women's characteristics on their willingness to join a blind or a non-blind subtrial or to be excluded by physicians. DESIGN: Primary prevention trial of postmenopausal hormone therapy (HT). A ... -
Geenin periytyvyys ja syövän perimä
Hakama, Matti; Malila, Nea; Rantanen, Matti; Pitkäniemi, Janne (2017)
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Kokeelliset tutkimukset sosiaalilääketieteessä
Hemminki, Elina; Malila, Nea; Hakama, Matti (2014)
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Results from a blind and a non-blind randomised trial run in parallel: experience from the Estonian Postmenopausal Hormone Therapy (EPHT) Trial
Veerus, Piret; Fischer, Krista; Hakama, Matti; Hemminki, Elina; The, EPHT Trial (2012)
articleBackground The Estonian Postmenopausal Hormone Therapy (EPHT) Trial assigned 4170 potential participants prior to recruitment to blind or non-blind hormone therapy (HT), with placebo or non-treatment the respective ... -
Risk of gastric cancer in Helicobacter pylori infection in a 15-year follow-up
Vohlonen, Ilkka; Pukkala, Eero; Malila, Nea; Härkönen, Matti; Hakama, Matti; Koistinen, Veli; Sipponen, Pentti (2016)
articleObjective: We investigated the risk of gastric cancer among men with Helicobacter pylori (H. pylori) infection or atrophic gastritis (AG) in a 15-year follow-up. Materials and methods: Study population consists of 12,016 ... -
Survival of Patients With Cervical Cancer in Rural India
Vinoda Thulaseedharan, Jissa; Malila, Nea; Swaminathan, Rajaraman; Esmy Pulikottil, Okuru; Hakama, Matti; Muwonge, Richard; Sankaranarayanan, Rengaswamy (2015)
articleBackground: Patients’ survival after diagnosis of cervical cancer is indirectly influenced by socio-economic factors. We evaluated this survival and its socio-economic determinants in a rural population in south India. Methods: ... -
Tobacco use or body mass - do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study
Pednekar, Mangesh S; Hakama, Matti; Grupta, Prakash C (2012)
articleTobacco use and under-nutrition are major public health concerns and tuberculosis is a major cause of morbidity and mortality in India. Using a cohort of 148,173 persons (recruited 1991–1997 and followed-up 1997–2003) the ... -
Use of hospital resources in the Finnish colorectal cancer screening programme: a randomised health services study
Mäklin, Suvi; Hakama, Matti; Rissanen, Pekka; Malila, Nea (2015)
articleObjective To estimate the difference in use of hospital resources in the Finnish Colorectal Cancer (CRC) screening programme between those invited and controls, within the year of randomisation and the next year. Design CRC ... -
Who wants to join preventive trials? Experience from the Estonian Postmenopausal Hormone Therapy Trial [ISRCTN35338757]
Hovi, Sirkka-Liisa; Hakama, Matti; Veerus, Piret; Rahu, Mati; Hemminki, Elina (2005)
articleBackground The interest of patients in participating in randomized clinical trials involving treatments has been widely studied, but there has been much less research on interest in preventive trials. The objective of ...