Cold sprayed coatings in biomedicine
Ketola, Jonne Jalmari (2014)
Ketola, Jonne Jalmari
2014
Materiaalitekniikan koulutusohjelma
Teknisten tieteiden tiedekunta - Faculty of Engineering Sciences
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Hyväksymispäivämäärä
2014-12-03
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:tty-201412031571
https://urn.fi/URN:NBN:fi:tty-201412031571
Tiivistelmä
Cold spraying is an emerging coating technology with a unique and distinctive coating characteristics. The major advantages of the coatings fabricated using this solid-state deposition technology owe to low processing temperature and extreme particle velocity, resulting in dense and high-purity coating structures with a well-defined footprint and a wide range of attainable thicknesses. It has recently been a subject for increasing number of studies on potential medical applications. The majority of the cold spray studies are focused on improving the properties of orthopaedic implants but some other medically-driven research topics such as photocatalysis are current. However, in a clinical setting, implant rupture, aseptic loosening, inflammatory reactions, and material dissolution are common challenges of not only coated but of all the implants. As to coating technologies, there are several effective ways to overcome some of these problems, e.g., enhancing the bonding at the coating-substrate interface, preventing inflammatory reactions by means of antibacterial agents, eliminating the substrate from body fluid, or potentiating controlled drug release. In the context of cold spraying, the recent advances include fabrication of antimicrobial coatings, avoidance of a detrimental stress shielding –effect, and spraying of temperature-sensitive materials, such as magnesium, titania, hydroxyapatite, polymers and composite substrates. In terms of biocompatibility, also surface charge, porosity, and surface topography are central although little attention has been invested on them.
This thesis work is a literature survey on the present status and the future prospects of the cold sprayed coatings in the field of biomedicine. Therefore, the more specific objective was to produce a comprehensive review on potential materials and properties, and for that reason, a wide range of authors have been referenced. However, it was found that cold sprayed coating displayed good adhesion whereas fatigue strength, remained low. In biomedical terms, cold spraying was found as a coating method diversely capable of modifying cell response and tissue growth.
This thesis work is a literature survey on the present status and the future prospects of the cold sprayed coatings in the field of biomedicine. Therefore, the more specific objective was to produce a comprehensive review on potential materials and properties, and for that reason, a wide range of authors have been referenced. However, it was found that cold sprayed coating displayed good adhesion whereas fatigue strength, remained low. In biomedical terms, cold spraying was found as a coating method diversely capable of modifying cell response and tissue growth.