Impact of lipid based nutrient supplements (lns) on child sleep in rural Malawi : a randomized control trial
Phiri, Enita (2016)
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Phiri, Enita
2016
Master's Degree Programme in Health Sciences
Terveystieteiden yksikkö - School of Health Sciences
Hyväksymispäivämäärä
2016-04-04
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:uta-201611032499
https://urn.fi/URN:NBN:fi:uta-201611032499
Tiivistelmä
Background: Evidence indicates that Lipid-Based Nutrient Supplements (LNS) are associated with improved growth and development among infants but its role on child sleep patterns expressed through daytime naps, nighttime sleep duration and wake up times has not been tested in a randomized LNS trial.
Objective: The objective was to test the hypotheses that infants receiving complementary foods supplemented with LNS from 6 months to 18 months of age would have more daytime naps, longer nighttime sleep duration and wake up less at night than the infants receiving no supplementation.
Methods: This study was part of the International Lipid-based Nutrient Supplements (iLiNS) DYAD-M trial consisting of 869 pregnant women randomly assigned to one of the three intervention arms (LNS, Multiple Micronutrient Supplements (MMN), and Iron Folic Acid (IFA). A total of 879 children born to these women formed a sample for this study. Children in the LNS group (intervention group) received two sachets of LNS-20gM (20g of LNS) daily from 6 to 18 months of age whereas those in the IFA and MMN groups (control group) received nothing. Statistical analyses were performed in Stata version Stata 12.1 (StataCorp LP). t-test was used to compare daytime naps, nighttime sleep duration and wake up times between the intervention and control groups. Primary outcome for the present study was child sleep patterns between 6 to 18 months.
Results: Maternal and infant baseline characteristics were similar between the intervention and control groups. The mean (SD) number of daytime naps during the entire follow-up were, 1.77(±0.83) and 1.73(±0.81) per day in the intervention and control groups respectively (difference 0.04, 95%CI 0.00 to 0.08, P= 0.02). The mean (SD) hours of nighttime sleep duration during the entire follow-up were, 10.73 (1.21) and 10.72(1.21) per day for the LNS and control groups respectively (difference 0.01, 95%CI -0.05 to 0.07 P= 0.36). The mean (SD) number of wake up times during the entire follow up was 2.24 (±1.07) for intervention group and 2.24 (±1.06) for the control group per day (difference -0.00, 95%CI -0.05 to 0.05 P=0.52).
Conclusions: The findings support the hypothesis that children who received complementary foods supplemented with LNS from 6 to 18 months would have more daytime naps than the children who did not receive the supplement in rural Malawi. However the hypotheses that children who received complementary foods supplemented with LNS from 6 to 18 months would have longer night time sleep duration and wake up less often at night than the children who did not receive the supplement in rural Malawi were not supported by the findings. We therefore suggest that Lipid based nutrient supplements (LNS) partly have an impact on the child sleep patterns.
Objective: The objective was to test the hypotheses that infants receiving complementary foods supplemented with LNS from 6 months to 18 months of age would have more daytime naps, longer nighttime sleep duration and wake up less at night than the infants receiving no supplementation.
Methods: This study was part of the International Lipid-based Nutrient Supplements (iLiNS) DYAD-M trial consisting of 869 pregnant women randomly assigned to one of the three intervention arms (LNS, Multiple Micronutrient Supplements (MMN), and Iron Folic Acid (IFA). A total of 879 children born to these women formed a sample for this study. Children in the LNS group (intervention group) received two sachets of LNS-20gM (20g of LNS) daily from 6 to 18 months of age whereas those in the IFA and MMN groups (control group) received nothing. Statistical analyses were performed in Stata version Stata 12.1 (StataCorp LP). t-test was used to compare daytime naps, nighttime sleep duration and wake up times between the intervention and control groups. Primary outcome for the present study was child sleep patterns between 6 to 18 months.
Results: Maternal and infant baseline characteristics were similar between the intervention and control groups. The mean (SD) number of daytime naps during the entire follow-up were, 1.77(±0.83) and 1.73(±0.81) per day in the intervention and control groups respectively (difference 0.04, 95%CI 0.00 to 0.08, P= 0.02). The mean (SD) hours of nighttime sleep duration during the entire follow-up were, 10.73 (1.21) and 10.72(1.21) per day for the LNS and control groups respectively (difference 0.01, 95%CI -0.05 to 0.07 P= 0.36). The mean (SD) number of wake up times during the entire follow up was 2.24 (±1.07) for intervention group and 2.24 (±1.06) for the control group per day (difference -0.00, 95%CI -0.05 to 0.05 P=0.52).
Conclusions: The findings support the hypothesis that children who received complementary foods supplemented with LNS from 6 to 18 months would have more daytime naps than the children who did not receive the supplement in rural Malawi. However the hypotheses that children who received complementary foods supplemented with LNS from 6 to 18 months would have longer night time sleep duration and wake up less often at night than the children who did not receive the supplement in rural Malawi were not supported by the findings. We therefore suggest that Lipid based nutrient supplements (LNS) partly have an impact on the child sleep patterns.