CMV and Immunosenescence: from basics to clinics
Solana, Rafael; Tarazona, Raquel; Aiello, Allison E; Hurme, Mikko (2013)
Solana, Rafael
Tarazona, Raquel
Aiello, Allison E
Hurme, Mikko
et al.2013
Immunity & Ageing 9
23
Lääketieteen yksikkö - School of Medicine
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Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:uta-201303121045
https://urn.fi/URN:NBN:fi:uta-201303121045
Kuvaus
BioMed Central open access
Tiivistelmä
Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most countries, it has been suggested that it drives or at least exacerbates “immunosenescence”. This contention remains controversial and was the primary subject of the Third International Workshop on CMV & Immunosenescence which was held in Cordoba, Spain, 15-16th March, 2012. Discussions focused on several main themes including the effects of CMV on adaptive immunity and immunosenescence, characterization of CMV-specific T cells, impact of CMV infection and ageing on innate immunity, and finally, most important, the clinical implications of immunosenescence and CMV infection. Here we summarize the major findings of this workshop.
Kokoelmat
- Artikkelit [6140]