Immunogenicity and Safety of a Third COVID-19 BNT162b2 mRNA Vaccine Dose in 5- to 11-Year Olds

-, -; Simões, Eric A.F.; Klein, Nicola P.; Sabharwal, Charu; Gurtman, Alejandra; Kitchin, Nicholas; Ukkonen, Benita; Korbal, Piotr; Zou, Jing; Xie, Xuping; Sarwar, Uzma N.; Xu, Xia; Lockhart, Stephen; Cunliffe, Luke; Lu, Claire; Ma, Hua; Swanson, Kena A.; Koury, Kenneth; Shi, Pei Yong; Cooper, David; Türeci, Ozlem; Jansen, Kathrin U.; Şahin, Uğur; Gruber, William C. (2023-03)
 
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-, -
Simões, Eric A.F.
Klein, Nicola P.
Sabharwal, Charu
Gurtman, Alejandra
Kitchin, Nicholas
Ukkonen, Benita
Korbal, Piotr
Zou, Jing
Xie, Xuping
Sarwar, Uzma N.
Xu, Xia
Lockhart, Stephen
Cunliffe, Luke
Lu, Claire
Ma, Hua
Swanson, Kena A.
Koury, Kenneth
Shi, Pei Yong
Cooper, David
Türeci, Ozlem
Jansen, Kathrin U.
Şahin, Uğur
Gruber, William C.
03 / 2023

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY
doi:10.1093/jpids/piad015
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Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:tuni-202309088041

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Peer reviewed
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<p>In this ongoing study, substantially increased ancestral SARSCoV-2 neutralizing responses were observed 1 month after a third 10-µg BNT162b2 dose given to 5 to 11-year olds versus neutralizing responses post-dose 2. After dose 3, increased neutralizing responses against Omicron BA.1 and BA.4/BA.5 strains were also observed. The safety/tolerability profile was acceptable.</p>
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