Influential Periods in Longitudinal Clinical Cardiovascular Health Scores
Krefman, Amy E.; Labarthe, Darwin; Greenland, Philip; Pool, Lindsay; Aguayo, Liliana; Juonala, Markus; Kähönen, Mika; Lehtimäki, Terho; Day, R. Sue; Bazzano, Lydia; Muggeo, Vito M.R.; Van Horn, Linda; Liu, Lei; Webber, Larry S.; Pahkala, Katja; Laitinen, Tomi T.; Raitakari, Olli; Lloyd-Jones, Donald M.; Allen, Norrina B. (2021-11-02)
Krefman, Amy E.
Labarthe, Darwin
Greenland, Philip
Pool, Lindsay
Aguayo, Liliana
Juonala, Markus
Kähönen, Mika
Lehtimäki, Terho
Day, R. Sue
Bazzano, Lydia
Muggeo, Vito M.R.
Van Horn, Linda
Liu, Lei
Webber, Larry S.
Pahkala, Katja
Laitinen, Tomi T.
Raitakari, Olli
Lloyd-Jones, Donald M.
Allen, Norrina B.
02.11.2021
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:tuni-202201271668
https://urn.fi/URN:NBN:fi:tuni-202201271668
Kuvaus
Peer reviewed
Tiivistelmä
The prevalence of ideal cardiovascular health (CVH) among adults in the United States is low and decreases with age. Our objective was to identify specific age windows when the loss of CVH accelerates, to ascertain preventive opportunities for intervention. Data were pooled from 5 longitudinal cohorts (Project Heartbeat!, Cardiovascular Risk in Young Finns Study, The Bogalusa Heart Study, Coronary Artery Risk Development in Young Adults, Special Turku Coronary Risk Factor Intervention Project) from the United States and Finland from 1973 to 2012. Individuals with clinical CVH factors (i.e., body mass index, blood pressure, cholesterol, blood glucose) measured from ages 8 to 55 years were included. These factors were categorized and summed into a clinical CVH score ranging from 0 (worst) to 8 (best). Adjusted, segmented, linear mixed models were used to estimate the change in CVH over time. Among the 18,343 participants, 9,461 (52%) were female and 12,346 (67%) were White. The baseline mean (standard deviation) clinical CVH score was 6.9 (1.2) at an average age of 17.6 (8.1) years. Two inflection points were estimated: at 16.9 years (95% confidence interval: 16.4, 17.4) and at 37.2 years (95% confidence interval: 32.4, 41.9). Late adolescence and early middle age appear to be influential periods during which the loss of CVH accelerates.
Kokoelmat
- TUNICRIS-julkaisut [19236]