Stapled vs handsewn anastomosis and anastomotic leaks in gastric cancer surgery : a population-based nationwide study in Finland
Kvist, Elina; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Jalkanen, Aapo; Junttila, Anna; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Louhimo, Johanna; Meriläinen, Sanna; Pohjanen, Vesa Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V.; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H. (2024)
Kvist, Elina
Helminen, Olli
Helmiö, Mika
Huhta, Heikki
Jalkanen, Aapo
Junttila, Anna
Kallio, Raija
Koivukangas, Vesa
Kokkola, Arto
Laine, Simo
Lietzen, Elina
Louhimo, Johanna
Meriläinen, Sanna
Pohjanen, Vesa Matti
Rantanen, Tuomo
Ristimäki, Ari
Räsänen, Jari V.
Saarnio, Juha
Sihvo, Eero
Toikkanen, Vesa
Tyrväinen, Tuula
Valtola, Antti
Kauppila, Joonas H.
2024
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:tuni-202406127148
https://urn.fi/URN:NBN:fi:tuni-202406127148
Kuvaus
Peer reviewed
Tiivistelmä
Background: There is a lack of evidence regarding anastomotic technique and postoperative complications in gastric cancer surgery. This study aimed to evaluate whether there are differences between stapled and handsewn anastomosis and anastomotic leaks. Methods: This was a population-based, retrospective, nationwide cohort study in Finland using the Finnish National Esophago-Gastric Cancer Cohort. Patients undergoing gastrectomy with available postoperative complication data were included. Logistic regression analysis was used to calculate the odds ratios with 95% CIs, adjusted for calendar period of surgery, age at surgery, sex, comorbidity, tumor stage, neoadjuvant therapy, minimally invasive surgery, type of gastrectomy, radical resection, and type of anastomosis. Results: Of the 2164 patients, 472 of all patients (21.8%) had handsewn anastomosis and 1692 of all patients (78.2%) had stapled anastomosis. In the unadjusted analysis, anastomotic leaks were significantly lower in the handsewn group (hazard ratio [HR], 0.42; 95% CI, 0.22-0.79) than the stapled group, but after adjustment for known prognostic factors, this association was no longer significant (HR, 0.57; 95% CI, 0.27-1.21). In the analysis stratified by gastrectomy type (distal or total), no differences in anastomotic leaks were observed between anastomotic techniques. Conclusion: In this population-based nationwide study, anastomotic technique (stapled or handsewn) was not associated with anastomotic leaks in any, distal or total, gastrectomy.
Kokoelmat
- TUNICRIS-julkaisut [19236]