Schizophrenia polygenic risk score and long-term success in the labour market : A cohort study
Viinikainen, Jutta; Böckerman, Petri; Hakulinen, Christian; Kari, Jaana T.; Lehtimäki, Terho; Raitakari, Olli T.; Pehkonen, Jaakko (2022-07)
Viinikainen, Jutta
Böckerman, Petri
Hakulinen, Christian
Kari, Jaana T.
Lehtimäki, Terho
Raitakari, Olli T.
Pehkonen, Jaakko
07 / 2022
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:tuni-202208156393
https://urn.fi/URN:NBN:fi:tuni-202208156393
Kuvaus
Peer reviewed
Tiivistelmä
Employment is rare among people with a schizophrenia diagnosis. Meanwhile, a genetic liability for schizophrenia may hinder labour market performance. We studied how the polygenic risk score (PGS) for schizophrenia related to education and labour market outcomes. We found that a higher PGS was linked to lower educational levels and weaker labour market outcomes as well as a higher likelihood of receiving social income transfers, particularly among men. Assuming that the link is causal, our results indicate that individuals with schizophrenia or schizophrenia-related traits have a weakened ability to fully participate in the labour market, potentially reinforcing social exclusion.
Kokoelmat
- TUNICRIS-julkaisut [16977]