O,O-Silyl Group Migrations in Quinic Acid Derivatives : An Opportunity for Divergent Synthesis
Holmstedt, Suvi; Efimov, Alexander; Candeias, Nuno R. (2021)
Candeias, Nuno R.
This publication is copyrighted. You may download, display and print it for Your own personal use. Commercial use is prohibited
Julkaisun pysyvä osoite on
The O,O-silyl group migrations on a quinic acid-derived cyclitol have been studied, and the ease of migration was observed to be dependent on the silicon substituents and reaction conditions. Conditions were found to improve the formation of a main isomer during the O,O-silyl group migrations that could be integrated into the formal synthesis of vitamin D receptor modulator VS-105 and in the first total synthesis of a metabolite from the African ant Crematogaster nigriceps.
- TUNICRIS-julkaisut