Association between admission criteria and body composition among young children with moderate acute malnutrition, a cross-sectional study from Burkina Faso
Fabiansen, Christian; Cichon, Bernardette; Yaméogo, Charles W.; Iuel-Brockdorf, Ann-Sophie; Phelan, Kevin P. Q.; Wells, Jonathan C.; Ritz, Christian; Filteau, Suzanne; Briend, André; Christensen, Vibeke B.; Ashorn, Per; Michaelsen, Kim F.; Shepherd, Susan; Friis, Henrik (2020)
Fabiansen, Christian
Cichon, Bernardette
Yaméogo, Charles W.
Iuel-Brockdorf, Ann-Sophie
Phelan, Kevin P. Q.
Wells, Jonathan C.
Ritz, Christian
Filteau, Suzanne
Briend, André
Christensen, Vibeke B.
Ashorn, Per
Michaelsen, Kim F.
Shepherd, Susan
Friis, Henrik
2020
13266
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:tuni-202201041064
https://urn.fi/URN:NBN:fi:tuni-202201041064
Kuvaus
Peer reviewed
Tiivistelmä
Children with moderate acute malnutrition (MAM) are treated based on low weight‑for‑length z‑score (WLZ), low mid‑upper arm circumference (MUAc) or both. this study aimed to assess associations of admission criteria and body composition (Bc), to improve treatment of MAM. We undertook a cross-sectional study among 6–23 months old Burkinabe children with MAM. Fat-free (FFM) and fat mass (fM) were determined by deuterium dilution and expressed as ffM (ffMi) and fM index (fMi). Of 1,489 children, 439 (29.5%) were recruited by low MUAC only (MUAC-O), 734 (49.3%) by low WLZ and low MUAC (WLZ-MUAC) and 316 (21.2%) by low WLZ only (WLZ-O). Thus, 1,173 (78.8%) were recruited by low MUAC, with or without low WLZ (ALL-MUAC). After adjustments, WLZ-O had 89 g (95% confidence interval (CI) 5; 172) lower FFM compared to MUAC-O. Similarly, WLZ-O had 0.89 kg/m2 (95% CI 0.77; 1.01) lower FFMI compared to MUAC-O, whereas there was no difference for FMI. However, boys included by WLZ-O compared to MUAC-O had 0.21 kg/m2 (95% CI 0.05; 0.38) higher FMI. In contrast, girls included by WLZ-O had 0.17 (95% CI 0.01; 0.33) kg/m2 lower fMi compared to MUAC-O (interaction, p = 0.002). We found that different criteria for admission into MAM treatment programmes select children with differences in BC, especially FFMI. Trial registration: ISRCTN42569496.
Kokoelmat
- TUNICRIS-julkaisut [19011]