SARS-CoV-2 late shedding may be infectious between immunocompromised hosts
Kaila, Ville; Sirkeoja, Simo; Blomqvist, Soile; Rannikko, Juha; Viskari, Hanna; Lyly-Yrjänäinen, Tiina; Syrjänen, Jaana (2021)
Kaila, Ville
Sirkeoja, Simo
Blomqvist, Soile
Rannikko, Juha
Viskari, Hanna
Lyly-Yrjänäinen, Tiina
Syrjänen, Jaana
2021
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:tuni-202109247270
https://urn.fi/URN:NBN:fi:tuni-202109247270
Kuvaus
Non peer reviewed
Tiivistelmä
Background: Immunocompromised patients shed SARS-CoV-2 for extended periods, but to our knowledge person-to-person transmission from late shedding has not been reported. The case: We present a case in which a COVID-19 patient infected another over 28 days after the patient’s initial symptoms, past current guideline recommendations of 20 days for length of isolation in immunocompromised patients. Whole genome sequencing of their viruses was performed to ascertain the transmission. Discussion: Severely immunocompromised patients, whose clearance of the virus is impaired, may remain infectious for extended periods. Caution should be taken particularly in hospital settings where lapses in isolation procedures might pose increased risk, especially to other immunocompromised patients.
Kokoelmat
- TUNICRIS-julkaisut [16740]