Implant survival of 2,723 vitamin E-infused highly crosslinked polyethylene liners in total hip arthroplasty : data from the Finnish Arthroplasty Register
Hemmilä, Matias; Laaksonen, Inari; Matilainen, Markus; Eskelinen, Antti; Haapakoski, Jaason; Puhto, Ari Pekka; Kettunen, Jukka; Pamilo, Konsta; Mäkelä, Keijo T. (2021)
Hemmilä, Matias
Laaksonen, Inari
Matilainen, Markus
Eskelinen, Antti
Haapakoski, Jaason
Puhto, Ari Pekka
Kettunen, Jukka
Pamilo, Konsta
Mäkelä, Keijo T.
2021
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:tuni-202104304191
https://urn.fi/URN:NBN:fi:tuni-202104304191
Kuvaus
Peer reviewed
Tiivistelmä
Background and purpose — The use of crosslinked polyethylene in total hip arthroplasty (THA) has decreased wear remarkably. It has been suggested that the antioxidative effects of vitamin E may enhance the wear properties of polyethylene even further. This study evaluates revision rates between vitamin E-infused polyethylene liners (E1 and E-poly, ZimmerBiomet, Warsaw, IN, USA) versus moderately crosslinked polyethylene (ModXLPE) liners from the same manufacturer used in primary THA. Patients and methods — We conducted a study based on data from the Finnish Arthroplasty Register. The study group consisted of 2,723 THAs with a vitamin E-infused liner and a reference group of 2,707 THAs with a moderately crosslinked polyethylene liner. Survivorship, revision risk, and re-revision causes were compared between groups. Results — The 7-year survival of the vitamin E-infused polyethylene liner group and of the reference group with revision for any reason as the endpoint was comparable (94% [95% CI 92.9–94.9] and 93% [CI 91.9–93.9], respectively). The adjusted hazard ratio (HR) for any revision was similar between the groups (0.7 [CI 0.4–1.1]). When revision for aseptic loosening was studied as the endpoint, the survival for the study group was 99% (CI 98.6–99.4) and for the reference group 99% (CI 98.7–99.5), and the risk of revision was comparable between the study groups (HR 1.3 [CI 0.7–2.5]). Interpretation — After an observation period of 7 years vitamin E-infused liners shows results equal to results obtained with crosslinked polyethylene liners.
Kokoelmat
- TUNICRIS-julkaisut [16929]