"Ylä-Outinen, Laura" - Selaus tekijän mukaan TUNICRIS-julkaisut
Viitteet 1-8 / 8
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Advancing chemical safety assessment through an omics-based characterization of the test system-chemical interaction
(2023)
articleAssessing chemical safety is essential to evaluate the potential risks of chemical exposure to human health and the environment. Traditional methods relying on animal testing are being replaced by 3R (reduction, refinement, ... -
Bidirectional cell-matrix interaction dictates neuronal network formation in a brain-mimetic 3D scaffold
(2022)
articleHuman pluripotent stem cells (hPSC) derived neurons are emerging as a powerful tool for studying neurobiology, disease pathology, and modeling. Due to the lack of platforms available for housing and growing hPSC-derived ... -
Carbon nanotube micropillars trigger guided growth of complex human neural stem cells networks
(2019)
articleNew strategies for spatially controlled growth of human neurons may provide viable solutions to treat and recover peripheral or spinal cord injuries. While topography cues are known to promote attachment and direct ... -
Cell culture chamber with gas supply for prolonged recording of human neuronal cells on microelectrode array
(2017)
articleBackground Typically, live cell analyses are performed outside an incubator in an ambient air, where the lack of sufficient CO2 supply results in a fast change of pH and the high evaporation causes concentration drifts in ... -
Novel method to produce a layered 3D scaffold for human pluripotent stem cell-derived neuronal cells
(15.02.2021)
articleBACKGROUND: Three-dimensional (3D) in vitro models have been developed into more in vivo resembling structures. In particular, there is a need for human-based models for neuronal tissue engineering (TE). To produce such a ... -
Optimised PDMS tunnel devices on MEAs increase the probability of detecting electrical activity from human stem cell-derived neuronal networks
(2017)
articleMeasurement of the activity of human pluripotent stem cell (hPSC)-derived neuronal networks with microelectrode arrays (MEAs) plays an important role in functional in vitro brain modelling and in neurotoxicological screening. ... -
Simulation of developing human neuronal cell networks
(2016)
articleBackground: Microelectrode array (MEA) is a widely used technique to study for example the functional properties of neuronal networks derived from human embryonic stem cells (hESC-NN). With hESC-NN, we can investigate the ... -
Structured PDMS chambers for enhanced human neuronal cell activity on MEA platforms
(2012)
articleStructured poly(dimethylsiloxane) (PDMS) chambers were designed and fabricated to enhance the signaling of human embryonic stem cell (hESC) - derived neuronal networks on microelectrode array (MEA) platforms. The structured ...
