TUNICRIS-julkaisut - Trepo

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A randomized, double-blind, placebo-controlled, dose-escalating phase I trial to evaluate safety and immunogenicity of a plant-produced, bivalent, recombinant norovirus-like particle vaccine

Leroux-Roels, Isabel; Maes, Cathy; Joye, Jasper; Jacobs, Bart; Jarczowski, Franziska; Diessner, André; Janssens, Yorick; Waerlop, Gwenn; Tamminen, Kirsi; Heinimäki, Suvi; Blazevic, Vesna; Leroux-Roels, Geert; Klimyuk, Victor; Adachi, Hiroshi; Hiruta, Kazuyuki; Thieme, Frank (07.10.2022)
article

<p>Noroviruses (NoV) are the leading cause of epidemic acute gastroenteritis in humans worldwide and a safe and effective vaccine is needed. Here, a phase I, double-blind, placebo-controlled clinical trial was performed ...