"Tolonen, Teemu" - Selaus tekijän mukaan TUNICRIS-julkaisut
Viitteet 1-19 / 19
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Breast density and the likelihood of malignant MRI-detected lesions in women diagnosed with breast cancer
(2023)
articleObjectives: To assess whether mammographic breast density in women diagnosed with breast cancer correlates with the total number of incidental magnetic resonance imaging (MRI)-detected lesions and the likelihood of the ... -
Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine
(10 / 2023)
articleBackground: Prostate cancer (PrCa) genomic heterogeneity causes resistance to therapies such as androgen deprivation. Such heterogeneity can be deciphered in the context of evolutionary principles, but current clinical ... -
Combined Longitudinal Clinical and Autopsy Phenomic Assessment in Lethal Metastatic Prostate Cancer: Recommendations for Advancing Precision Medicine
(08 / 2021)
article<p>Background: Systematic identification of data essential for outcome prediction in metastatic prostate cancer (mPC) would accelerate development of precision oncology. Objective: To identify novel phenotypes and ... -
Differential mobility spectrometry imaging for pathological applications
(01.12.2020)
article<p>Pathologic examination of clinical tissue samples is time consuming and often does not involve the comprehensive analysis of the whole specimen. Automated tissue analysis systems have potential to make the workflow ... -
Digitalization of pathology in a multicenter setup: A user experience study and comparison of two alternative implementation strategies
(08 / 2025)
articleBACKGROUND: Fimlab Laboratories and Turku University Hospital implemented digital pathology simultaneously but with different strategies. At Fimlab, all histological slides were scanned starting from the first go-live date, ... -
Evaluation of the Effect of Iodine Staining and Sodium Thiosulfate Clearing on the Quality of X-ray Microtomographic Images and Histological Processing of Small Bowel Biopsies
IFMBE Proceedings (2024)
conferenceHistological evaluation of small bowel biopsies remains the gold standard diagnostic and follow-up outcome in celiac disease. X-ray microtomography (µCT) has been introduced as a complementary imaging tool to assess ... -
Expected impact of MRI-targeted biopsy interreader variability among uropathologists on ProScreen prostate cancer screening trial: a pre-trial validation study
(2024)
articlePurpose: Prostate cancer (PCa) histology, particularly the Gleason score, is an independent prognostic predictor in PCa. Little is known about the inter-reader variability in grading of targeted prostate biopsy based on ... -
The Impact of Atorvastatin on Intraprostatic Biomarkers – Prognostic Value of 3LS-score: Follow-up of ESTO1-Trial
(03 / 2025)
articleBackground: Prostate cancer (PCa) remains a global health burden, with limited reliable biomarkers beyond prostate-specific antigen (PSA). Statins have been associated with survival benefits in advanced Pca, potentially ... -
Keloid vasculature reacts to intralesional injection therapies but does not predict the response to treatment: Biopsies from double-blinded, randomized, controlled trial
(06 / 2025)
articleKeloids are benign fibroproliferative skin scars that expand beyond the original wound site. Hypoxia and angiogenesis are thought to drive pathological scar formation in keloids. We utilized biopsies collected before, ... -
Kivessyövän hoito
(10.03.2021)
reviewarticleKivessyöpä on tavallisin nuorten miesten syöpä. Sen ilmaantuvuus lisääntyy. Taudin varhainen toteaminen perusterveydenhuollossa on tärkeää, vaikka levinneenkin syövän ennuste on hyvä. Hoidot on keskitetty yliopistosairaaloihin. ... -
Laser desorption tissue imaging with Differential Mobility Spectrometry
(04 / 2022)
article<p>Pathological gross examination of breast carcinoma samples is sometimes laborious. A tissue pre-mapping method could indicate neoplastic areas to the pathologist and enable focused sampling. Differential Mobility ... -
Micro-computed Tomography in the Evaluation of Eosin-stained Axillary Lymph Node Biopsies of Females Diagnosed with Breast Cancer
(11 / 2024)
articleHistopathological investigation of metastasis in core needle axillary lymph node (ALN) biopsies is crucial for the prognosis and treatment planning of breast cancer patients. Biopsies are typically sliced and evaluated as ... -
A Novel X-Ray 3D Histological Method for Paraffinated Prostate Samples
IFMBE Proceedings (2024)
conferenceProstate cancer grading currently relies on the histopathological assessment of biopsies, which are analyzed as histological slides. However, the inherent two-dimensional (2D) nature of this approach, along with the limited ... -
Population-based randomized trial of screening for clinically significant prostate cancer ProScreen: a pilot study
(2021)
articleObjectives: To evaluate the feasibility of a population-based screening trial using prostate-specific antigen (PSA), a kallikrein panel and multiparametric magnetic resonance imaging (MRI) aimed at minimizing overdiagnosis, ... -
Prostate Cancer Screening with PSA, Kallikrein Panel, and MRI: The ProScreen Randomized Trial
(2024)
articleImportance: Prostate-specific antigen (PSA) screening has potential to reduce prostate cancer mortality but frequently detects prostate cancer that is not clinically important. Objective: To describe rates of low-grade ... -
Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer
(11 / 2024)
articleProstate cancer treatment resistance is a significant challenge facing the field. Genomic and transcriptomic profiling have partially elucidated the mechanisms through which cancer cells escape treatment, but their relation ... -
A systematic approach to study the effects of acquisition parameters and biological factors on computerized mammography analysis using ex vivo human tissue: A protocol description
(08 / 2025)
articleBackground: Mammography is the most common imaging modality for the detection of breast cancer. Artificial intelligence algorithms for mammography analysis have shown promising performance for breast cancer risk assessment ...
