"Taavitsainen, S." - Selaus tekijän mukaan TUNICRIS-julkaisut

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    • Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy 

      Woodcock, D. J.; Riabchenko, E.; Taavitsainen, S.; Kankainen, M.; Gundem, G.; Brewer, D. S.; Ellonen, P.; Lepistö, M.; Golubeva, Y. A.; Warner, A. C.; Tolonen, T.; Jasu, J.; Isaacs, W. B.; Emmert-Buck, M. R.; Nykter, M.; Visakorpi, T.; Bova, G. S.; Wedge, D. C. (2020)
      article
      The evolutionary progression from primary to metastatic prostate cancer is largely uncharted, and the implications for liquid biopsy are unexplored. We infer detailed reconstructions of tumor phylogenies in ten prostate ...

    • Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse 

      Taavitsainen, S.; Engedal, N.; Cao, S.; Handle, F.; Erickson, A.; Prekovic, S.; Wetterskog, D.; Tolonen, T.; Vuorinen, E. M.; Kiviaho, A.; Nätkin, R.; Häkkinen, T.; Devlies, W.; Henttinen, S.; Kaarijärvi, R.; Lahnalampi, M.; Kaljunen, H.; Nowakowska, K.; Syvälä, H.; Bläuer, M.; Cremaschi, P.; Claessens, F.; Visakorpi, T.; Tammela, T. L.J.; Murtola, T.; Granberg, K. J.; Lamb, A. D.; Ketola, K.; Mills, I. G.; Attard, G.; Wang, W.; Nykter, M.; Urbanucci, A. (2021)
      article
      Prostate cancer is heterogeneous and patients would benefit from methods that stratify those who are likely to respond to systemic therapy. Here, we employ single-cell assays for transposase-accessible chromatin (ATAC) and ...