"Taavela, Juha" - Selaus tekijän mukaan TUNICRIS-julkaisut
Viitteet 1-20 / 22
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Abdominal Bloating and Distension: Common Symptoms but Limited Evidence
(11 / 2025)
editorial -
Bulb biopsies for diagnosing celiac disease in children: A prospective multicenter study using quantitative histomorphometry
(01 / 2025)
articleObjectives: Duodenal bulb specimens are recommended for the diagnostic evaluation of celiac disease (CeD). However, it remains unclear if their quality and histomorphometry measures are comparable to samples obtained from ... -
Celiac disease antibody levels reflect duodenal mucosal damage but not clinical symptoms
(03 / 2021)
articleObjectives: This study aimed to investigate, in a real-world population, whether the histological and clinical phenotype differ at baseline and during follow-up in patients with high and low CD (celiac disease) antibody ... -
From Recommendation to Reality: The Follow-Up Gap in Coeliac Disease
(04 / 2026)
editorial -
Gluten Induces Subtle Histological Changes in Duodenal Mucosa of Patients with Non-Coeliac Gluten Sensitivity: A Multicentre Study
(06 / 2022)
articleBackground: Histological changes induced by gluten in the duodenal mucosa of patients with non-coeliac gluten sensitivity (NCGS) are poorly defined. Objectives: To evaluate the structural and inflammatory features of NCGS ... -
Healthy and pro-inflammatory gut ecology plays a crucial role in the digestion and tolerance of a novel Gluten Friendly™ bread in celiac subjects: Randomized, double blind, placebo control in vivo study
(07.02.2022)
articleGluten Friendly™ (GF) is a new gluten achieved through a physicochemical process applied to wheat kernels. The goal of this research was to assess the in vivo effects of Gluten Friendly™ bread on celiac gut mucosa and ... -
Iron transporter protein expressions in children with celiac disease
(02 / 2021)
articleAnemia is a frequent finding in children with celiac disease but the detailed pathophysiological mechanisms in the intestine remain obscure. One possible explanation could be an abnormal expression of duodenal iron transport ... -
Keliakiaan liittymätön gluteeniherkkyys: mistä on kyse?
(2021)
reviewarticle -
Keliakian esiintyvyys Suomessa lisääntyy yhä
(2024)
article -
Long-term health outcomes of people without celiac disease avoiding gluten consumption: a 25-year prospective cohort study
(10 / 2025)
articleBackground: Self-reported abdominal symptoms after consuming gluten-containing cereals in individuals without celiac disease (CeD) are common. The long-term outcomes of these individuals are unknown. Methods: Seventy-six ... -
A New Intraepithelial γδ T-Lymphocyte Marker for Celiac Disease Classification in Formalin-Fixed Paraffin-Embedded (FFPE) Duodenal Biopsies
(03.11.2020)
articleBackground: The histopathologic diagnosis of celiac disease (CD) may be challenging when the duodenal biopsies mucosal injury is limited. Intraepithelial T-lymphocytes (IELs) can be useful to characterize the degree of ... -
Prevalence and characteristics of adults avoiding gluten without celiac disease: a long-term population-based follow-up study
(03 / 2025)
articleObjective: Nationwide prevalence studies on people avoiding gluten without celiac disease (PWAG) are lacking, and in particular, long-term follow-up studies are unavailable. We aimed to evaluate the prevalence, incidence, ... -
A randomized trial of a transglutaminase 2 inhibitor for celiac disease
(01.07.2021)
articleBACKGROUND In celiac disease, small intestinal transglutaminase 2 causes deamidation of glutamine residues in gluten peptides, which enhances stimulation of T cells and leads to mucosal injury. Inhibition of transglutaminase ... -
Screen-Detected Coeliac Disease in a Nationally Representative Cohort: Health Indicators, Long-Term Outcomes and Mortality
(2026)
articleBackground: Population-based screening for coeliac disease could reduce underdiagnosis, but benefits and harms remain debated. Aim: We studied health outcomes in screen-detected coeliac disease patients at diagnosis and ... -
Transcriptomic analysis of intestine following administration of a transglutaminase 2 inhibitor to prevent gluten-induced intestinal damage in celiac disease
(2024)
articleTransglutaminase 2 (TG2) plays a pivotal role in the pathogenesis of celiac disease (CeD) by deamidating dietary gluten peptides, which facilitates antigenic presentation and a strong anti-gluten T cell response. Here, we ... -
Trends in the prevalence rates and predictive factors of coeliac disease: A long-term nationwide follow-up study
(2023)
articleBackground: The prevalence of coeliac disease doubled in Finland from 1980 to 2000. Aims: To investigate whether this increase is continuing and if there are specific patient-related factors predicting the development of ... -
Upcoming Treatments in Celiac Disease: From Luminal Enzymes to Oral Immune Tolerance
(04 / 2026)
reviewarticleCeliac disease (CeD) is a chronic autoimmune enteropathy triggered by dietary gluten in genetically predisposed individuals. Currently, a gluten-free diet (GFD) is the only available treatment, being effective in improving ...
