"Svergun, Dmitri" - Selaus tekijän mukaan TUNICRIS-julkaisut

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    • The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering 

      Kukkurainen, Sampo; Azizi, Latifeh; Zhang, Pingfeng; Jacquier, Marie Claude; Baikoghli, Mo; von Essen, Magdaléna; Tuukkanen, Anne; Laitaoja, Mikko; Liu, Xiaonan; Rahikainen, Rolle; Orłowski, Adam; Jänis, Janne; Määttä, Juha A. E.; Varjosalo, Markku; Vattulainen, Ilpo; Róg, Tomasz; Svergun, Dmitri; Cheng, R. Holland; Wu, Jinhua; Hytönen, Vesa P.; Wehrle-Haller, Bernhard (12.10.2020)
      article
      Integrin activation and clustering by talin are early steps of cell adhesion. Membrane-bound talin head domain and kindlin bind to the β integrin cytoplasmic tail, cooperating to activate the heterodimeric integrin, and ...

    • Structural basis of CDNF interaction with the UPR regulator GRP78 

      Graewert, Melissa A.; Volkova, Maria; Jonasson, Klara; Määttä, Juha A.E.; Gräwert, Tobias; Mamidi, Samara; Kulesskaya, Natalia; Evenäs, Johan; Johnsson, Richard E.; Svergun, Dmitri; Bhattacharjee, Arnab; Huttunen, Henri J. (12 / 2024)
      article
      Cerebral dopamine neurotrophic factor (CDNF) is an unconventional neurotrophic factor that is a disease-modifying drug candidate for Parkinson’s disease. CDNF has pleiotropic protective effects on stressed cells, but its ...