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Toxicogenomic assessment of in vitro macrophages exposed to profibrotic challenge reveals a sustained transcriptomic immune signature

Morikka, Jack; Federico, Antonio; Möbus, Lena; Inkala, Simo; Pavel, Alisa; Sani, Saara; Vaani, Maaret; Peltola, Sanna; Serra, Angela; Greco, Dario (12 / 2024)
article

Immune signalling is a crucial component in the progression of fibrosis. However, approaches for the safety assessment of potentially profibrotic substances, that provide information on mechanistic immune responses, are ...