"Rounioja, Samuli" - Selaus tekijän mukaan TUNICRIS-julkaisut

    • Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish 

      Saralahti, Anni K.; Harjula, Sanna Kaisa E.; Rantapero, Tommi; Uusi-Mäkelä, Meri I.E.; Kaasinen, Mikko; Junno, Maiju; Piippo, Hannaleena; Nykter, Matti; Lohi, Olli; Rounioja, Samuli; Parikka, Mataleena; Rämet, Mika (09.01.2023)
      article
      Streptococcus pneumoniae (pneumococcus) is one of the most frequent causes of pneumonia, sepsis and meningitis in humans, and an important cause of mortality among children and the elderly. We have previously reported the ...
    • Expression of BCL6 in paediatric B-cell acute lymphoblastic leukaemia and association with prognosis 

      Mäkinen, Artturi; Nikkilä, Atte; Mehtonen, Juha; Teppo, Susanna; Oksa, Laura; Nordlund, Jessica; Rounioja, Samuli; Pohjolainen, Virva; Laukkanen, Saara; Heinäniemi, Merja; Paavonen, Timo; Lohi, Olli (2021)
      article
      B-cell lineage acute lymphoblastic leukaemia (B-ALL) is the most common paediatric malignancy. Transcription factor B-cell lymphoma 6 (BCL6) is essential to germinal centre formation and antibody affinity maturation and ...
    • Myelodysplastinen oireyhtymä - monimuotoinen kirjo verisairauksia 

      Kauppila, Marjut; Holopainen, Annasofia; Kontro, Mika; Kytölä, Sari; Lehto, Minna; Laine, Outi; Myllymäki, Mikko; Rounioja, Samuli; Siitonen, Timo; Ebeling, Freja (2023)
      review
      Myelodysplastisissa oireyhtymissä (MDS) luuytimen verisolujen tuotanto on tehotonta ja verisolujen määrä vähenee. Yleisin verenkuvalöydös on normo- tai makrosyyttinen anemia. Taudilla on alttius muuttua leukemiaksi. Diagnoosi ...
    • Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities 

      Mehtonen, Juha; Teppo, Susanna; Lahnalampi, Mari; Kokko, Aleksi; Kaukonen, Riina; Oksa, Laura; Bouvy-Liivrand, Maria; Malyukova, Alena; Mäkinen, Artturi; Laukkanen, Saara; Mäkinen, Petri I.; Rounioja, Samuli; Ruusuvuori, Pekka; Sangfelt, Olle; Lund, Riikka; Lönnberg, Tapio; Lohi, Olli; Heinäniemi, Merja (2020)
      article
      Background: Tight regulatory loops orchestrate commitment to B cell fate within bone marrow. Genetic lesions in this gene regulatory network underlie the emergence of the most common childhood cancer, acute lymphoblastic ...