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Long-term real-world effectiveness and safety of fremanezumab in 1140 patients with migraine and at least 6 months of treatment: third interim analysis of the pan-European PEARL study

Ashina, Messoud; Mitsikostas, Dimos D.; Amin, Faisal Mohammad; Kokturk, Pinar; Schankin, Christoph J.; Sahin, Gurdal; Pozo-Rosich, Patricia; Dorman, Paul J.; Nežádal, Tomáš; Poole, Anne Christine; Martins, Isabel Pavão; Sumelahti, Marja Liisa; Ramirez Campos, Verena; Ahn, Andrew H.; Akcicek, Hasan; Tassorelli, Cristina (12 / 2025)
article

Introduction: Real-world data on the long-term use of fremanezumab for migraine prevention remain limited. This third interim analysis of the PEARL study addresses this gap by investigating the long-term effectiveness, ...
Real-world effectiveness of fremanezumab for the preventive treatment of migraine: Interim analysis of the pan-European, prospective, observational, phase 4 PEARL study

Ashina, Messoud; Mitsikostas, Dimos D.; Amin, Faisal Mohammad; Kokturk, Pinar; Schankin, Christoph J.; Sahin, Gurdal; Pozo-Rosich, Patricia; Dorman, Paul J.; Nežádal, Tomáš; Poole, Anne Christine; Martins, Isabel Pavão; Sumelahti, Marja-Liisa; Ramirez Campos, Verena; Ahn, Andrew H.; Lyras, Leonidas; Tassorelli, Cristina (01.11.2023)
article

BACKGROUND: The ongoing Pan-European Real Life (PEARL) phase 4 study is evaluating fremanezumab effectiveness and safety for the prevention of episodic and chronic migraine. This interim analysis reports primary, secondary ...