"Paakinaho, Ville" - Selaus tekijän mukaan TUNICRIS-julkaisut

Viitteet 1-3 / 3

    • Chromatin-directed proteomics-identified network of endogenous androgen receptor in prostate cancer cells 

      Launonen, Kaisa Mari; Paakinaho, Ville; Sigismondo, Gianluca; Malinen, Marjo; Sironen, Reijo; Hartikainen, Jaana M.; Laakso, Hanna; Visakorpi, Tapio; Krijgsveld, Jeroen; Niskanen, Einari A.; Palvimo, Jorma J. (2021)
      article
      <p>Treatment of prostate cancer confronts resistance to androgen receptor (AR)-targeted therapies. AR-associated coregulators and chromatin proteins hold a great potential for novel therapy targets. Here, we employed ...

    • Fanconi anemia pathway regulation by FANCI in prostate cancer 

      Kaljunen, Heidi; Taavitsainen, Sinja; Kaarijärvi, Roosa; Takala, Eerika; Paakinaho, Ville; Nykter, Matti; Bova, G Steven; Ketola, Kirsi (2023)
      article
      Prostate cancer is one of the leading causes of death among men worldwide, and thus, research on the genetic factors enabling the formation of treatment-resistant cancer cells is crucial for improving patient outcomes. ...

    • SUMOylation inhibition potentiates the glucocorticoid receptor to program growth arrest of acute lymphoblastic leukemia cells 

      Valima, Emma; Varis, Vera; Bureiko, Kseniia; Lempiäinen, Joanna K.; Schroderus, Anna Mari; Oksa, Laura; Lohi, Olli; Kinnunen, Tuure; Varjosalo, Markku; Niskanen, Einari A.; Paakinaho, Ville; Palvimo, Jorma J. (2025)
      article
      Glucocorticoids are a mainstay in the treatment of B-cell acute lymphoblastic leukemia (B-ALL). The glucocorticoid receptor (GR), a ligand-activated transcription factor (TF), mediates their actions. Chromatin occupancy, ...