"Niinikoski, Harri" - Selaus tekijän mukaan TUNICRIS-julkaisut

Viitteet 1-12 / 12

    • Association of Serum Trimethylamine-N-Oxide Concentration from Childhood to Early Adulthood with Age and Sex 

      Almer, Gunter; Enko, Dietmar; Kartiosuo, Noora; Niinikoski, Harri; Lehtimäki, Terho; Munukka, Eveliina; Viikari, Jorma; Rönnemaa, Tapani; Rovio, Suvi P.; Mykkänen, Juha; Lagström, Hanna; Jula, Antti; Herrmann, Markus; Raitakari, Olli T.; Meinitzer, Andreas; Pahkala, Katja (09 / 2024)
      article
      Background: Primary prevention is the cornerstone of cardiometabolic health. In the randomized, controlled Special Turku Coronary Risk Factor Intervention Project (STRIP), dietary counseling intervention was given to ...

    • Associations of long-term cumulative C-reactive protein and glycoprotein acetyls concentrations in childhood, adolescence and adulthood with adulthood retinal microvascular structure 

      Repo, Oskari; Juonala, Markus; Niinikoski, Harri; Rovio, Suvi; Mykkänen, Juha; Cheung, Carol Y.; Ala-Korpela, Mika; Vaahtoranta-Lehtonen, Hanna; Nevalainen, Jaakko; Jula, Antti; Kähönen, Mika; Lehtimäki, Terho; Laitinen, Tomi P.; Rönnemaa, Tapani; Viikari, Jorma; Raitakari, Olli; Tapp, Robyn; Pahkala, Katja (01 / 2025)
      article
      Backgroung and aims Inflammation is associated with cardiovascular disease development and microvascular dysfunction. The aim of the present study is to test the hypothesis that long-term exposure to chronic inflammation ...

    • Blood Pressure at Different Life Stages Over the Early Life Course and Intima-Media Thickness 

      Meng, Yaxing; Sharman, James E; Koskinen, Juhani S; Juonala, Markus; Viikari, Jorma S A; Buscot, Marie-Jeanne; Wu, Feitong; Fraser, Brooklyn J; Rovio, Suvi P; Kähönen, Mika; Rönnemaa, Tapani; Jula, Antti; Niinikoski, Harri; Raitakari, Olli T; Pahkala, Katja; Magnussen, Costan G (05.02.2023)
      article
      IMPORTANCE: Although cardiovascular disease (CVD) begins in early life, the extent to which blood pressure (BP) at different life stages contributes to CVD is unclear.OBJECTIVE: To determine the relative contribution of ...

    • Childhood exposure to parental smoking and life-course overweight and central obesity 

      Jaakkola, Johanna M; Rovio, Suvi P; Pahkala, Katja; Viikari, Jorma; Rönnemaa, Tapani; Jula, Antti; Niinikoski, Harri; Mykkänen, Juha; Juonala, Markus; Hutri-Kähönen, Nina; Kähönen, Mika; Lehtimäki, Terho; Raitakari, Olli T (2020)
      article
      <p>OBJECTIVE: To evaluate the association between childhood parental smoking exposure and the risk of overweight/obesity from childhood to adulthood.</p><p>METHODS: This study leverages the data from two ...

    • Determining the timing of pubertal onset via a multicohort analysis of growth 

      Syrjälä, Essi; Niinikoski, Harri; Virtanen, Helena E; Ilonen, Jorma; Knip, Mikael; Hutri-Kähönen, Nina; Pahkala, Katja; Raitakari, Olli; Rodprasert, Wiwat; Toppari, Jorma; Virtanen, Suvi; Veijola, Riitta; Peltonen, Jaakko; Nevalainen, Jaakko (18.11.2021)
      article

    • Earliest age to detect lifetime cardiometabolic health stratification in children 

      Mäkinen, Ville Petteri; Kähönen, Mika; Lehtimäki, Terho; Hutri, Nina; Rönnemaa, Tapani; Viikari, Jorma; Pahkala, Katja; Rovio, Suvi; Niinikoski, Harri; Mykkänen, Juha; Raitakari, Olli; Ala-Korpela, Mika (08 / 2026)
      article
      Background and aims Cardiovascular risk factors such as overweight and high cholesterol in childhood are predictive of high disease risk in adulthood. However, the optimal timing and scope of early prevention remains ...

    • Finnish-Enriched SLC26A7 Variant in Congenital Hypothyroidism: Clinical Spectrum, Thyroid Histopathology, and Expression Analysis 

      Niuro, Laura; Ojala, Johanna; Ravi, Rowmika; Melnyk, Vladyslav; Linnossuo, Veli; Palmu, Sofia; Jännäri, Meeri; Tyystjärvi, Sofia; Löf, Christoffer; Patyra, Konrad; Makkonen, Kristiina; Jääskeläinen, Jarmo; Danner, Emmi; Huopio, Hanna; Niinikoski, Harri; Viikari, Liisa; Kero, Andreina; Miettinen, Päivi; Schoenmakers, Nadia; Reeve, Mary Pat; Kero, Jukka (2026)
      article
      BACKGROUND: Defects in thyroid hormone synthesis at birth lead to congenital hypothyroidism (CH). Recently, pathogenic variants in the SLC26A7 gene have been linked to dyshormonogenetic goitrous CH. This anion transporter ...

    • Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis 

      Kanoni, Stavroula; Graham, Sarah E; Wang, Yuxuan; Surakka, Ida; Ramdas, Shweta; Zhu, Xiang; Clarke, Shoa L; Bhatti, Konain Fatima; Vedantam, Sailaja; Winkler, Thomas W; Locke, Adam E; Marouli, Eirini; Zajac, Greg J M; Wu, Kuan-Han H; Ntalla, Ioanna; Hui, Qin; Klarin, Derek; Hilliard, Austin T; Wang, Zeyuan; Xue, Chao; Thorleifsson, Gudmar; Helgadottir, Anna; Gudbjartsson, Daniel F; Holm, Hilma; Olafsson, Isleifur; Hwang, Mi Yeong; Han, Sohee; Akiyama, Masato; Sakaue, Saori; Terao, Chikashi; Kanai, Masahiro; Zhou, Wei; Brumpton, Ben M; Rasheed, Humaira; Havulinna, Aki S; Veturi, Yogasudha; Pacheco, Jennifer Allen; Rosenthal, Elisabeth A; Lingren, Todd; Feng, QiPing; Kullo, Iftikhar J; Narita, Akira; Takayama, Jun; Martin, Hilary C; Hunt, Karen A; Trivedi, Bhavi; Haessler, Jeffrey; Giulianini, Franco; Bradford, Yuki; Miller, Jason E; Campbell, Archie; Lin, Kuang; Millwood, Iona Y; Rasheed, Asif; Hindy, George; Faul, Jessica D; Zhao, Wei; Weir, David R; Turman, Constance; Huang, Hongyan; Graff, Mariaelisa; Choudhury, Ananyo; Sengupta, Dhriti; Mahajan, Anubha; Brown, Michael R; Zhang, Weihua; Yu, Ketian; Schmidt, Ellen M; Pandit, Anita; Gustafsson, Stefan; Yin, Xianyong; Luan, Jian'an; Zhao, Jing-Hua; Matsuda, Fumihiko; Jang, Hye-Mi; Yoon, Kyungheon; Medina-Gomez, Carolina; Pitsillides, Achilleas; Hottenga, Jouke Jan; Wood, Andrew R; Ji, Yingji; Gao, Zishan; Haworth, Simon; Yousri, Noha A; Mitchell, Ruth E; Chai, Jin Fang; Aadahl, Mette; Bjerregaard, Anne A; Yao, Jie; Manichaikul, Ani; Hwu, Chii-Min; Hung, Yi-Jen; Warren, Helen R; Ramirez, Julia; Bork-Jensen, Jette; Kårhus, Line L; Goel, Anuj; Sabater-Lleal, Maria; Noordam, Raymond; Mauro, Pala; Matteo, Floris; McDaid, Aaron F; Marques-Vidal, Pedro; Wielscher, Matthias; Trompet, Stella; Sattar, Naveed; Møllehave, Line T; Munz, Matthias; Zeng, Lingyao; Huang, Jianfeng; Yang, Bin; Poveda, Alaitz; Kurbasic, Azra; Lamina, Claudia; Forer, Lukas; Scholz, Markus; Galesloot, Tessel E; Bradfield, Jonathan P; Ruotsalainen, Sanni E; Daw, EWarwick; Zmuda, Joseph M; Mitchell, Jonathan S; Fuchsberger, Christian; Christensen, Henry; Brody, Jennifer A; Vazquez-Moreno, Miguel; Feitosa, Mary F; Wojczynski, Mary K; Wang, Zhe; Preuss, Michael H; Mangino, Massimo; Christofidou, Paraskevi; Verweij, Niek; Benjamins, Jan W; Engmann, Jorgen; Tsao, Noah L; Verma, Anurag; Slieker, Roderick C; Lo, Ken Sin; Zilhao, Nuno R; Le, Phuong; Kleber, Marcus E; Delgado, Graciela E; Huo, Shaofeng; Ikeda, Daisuke D; Iha, Hiroyuki; Yang, Jian; Liu, Jun; Demirkan, Ayşe; Leonard, Hampton L; Marten, Jonathan; Frank, Mirjam; Schmidt, Börge; Smyth, Laura J; Cañadas-Garre, Marisa; Wang, Chaolong; Nakatochi, Masahiro; Wong, Andrew; Hutri-Kähönen, Nina; Sim, Xueling; Xia, Rui; Huerta-Chagoya, Alicia; Fernandez-Lopez, Juan Carlos; Lyssenko, Valeriya; Nongmaithem, Suraj S; Bayyana, Swati; Stringham, Heather M; Irvin, Marguerite R; Oldmeadow, Christopher; Kim, Han-Na; Ryu, Seungho; Timmers, Paul R H J; Arbeeva, Liubov; Dorajoo, Rajkumar; Lange, Leslie A; Prasad, Gauri; Lorés-Motta, Laura; Pauper, Marc; Long, Jirong; Li, Xiaohui; Theusch, Elizabeth; Takeuchi, Fumihiko; Spracklen, Cassandra N; Loukola, Anu; Bollepalli, Sailalitha; Warner, Sophie C; Wang, Ya Xing; Wei, Wen B; Nutile, Teresa; Ruggiero, Daniela; Sung, Yun Ju; Chen, Shufeng; Liu, Fangchao; Yang, Jingyun; Kentistou, Katherine A; Banas, Bernhard; Nardone, Giuseppe Giovanni; Meidtner, Karina; Bielak, Lawrence F; Smith, Jennifer A; Hebbar, Prashantha; Farmaki, Aliki-Eleni; Hofer, Edith; Lin, Maoxuan; Concas, Maria Pina; Vaccargiu, Simona; van der Most, Peter J; Pitkänen, Niina; Cade, Brian E; van der Laan, Sander W; Chitrala, Kumaraswamy Naidu; Weiss, Stefan; Bentley, Amy R; Doumatey, Ayo P; Adeyemo, Adebowale A; Lee, Jong Young; Petersen, Eva R B; Nielsen, Aneta A; Choi, Hyeok Sun; Nethander, Maria; Freitag-Wolf, Sandra; Southam, Lorraine; Rayner, Nigel W; Wang, Carol A; Lin, Shih-Yi; Wang, Jun-Sing; Couture, Christian; Lyytikäinen, Leo-Pekka; Nikus, Kjell; Cuellar-Partida, Gabriel; Vestergaard, Henrik; Hidalgo, Bertha; Giannakopoulou, Olga; Cai, Qiuyin; Obura, Morgan O; van Setten, Jessica; Li, Xiaoyin; Liang, Jingjing; Tang, Hua; Terzikhan, Natalie; Shin, Jae Hun; Jackson, Rebecca D; Reiner, Alexander P; Martin, Lisa Warsinger; Chen, Zhengming; Li, Liming; Kawaguchi, Takahisa; Thiery, Joachim; Bis, Joshua C; Launer, Lenore J; Li, Huaixing; Nalls, Mike A; Raitakari, Olli T; Ichihara, Sahoko; Wild, Sarah H; Nelson, Christopher P; Campbell, Harry; Jäger, Susanne; Nabika, Toru; Al-Mulla, Fahd; Niinikoski, Harri; Braund, Peter S; Kolcic, Ivana; Kovacs, Peter; Giardoglou, Tota; Katsuya, Tomohiro; de Kleijn, Dominique; de Borst, Gert J; Kim, Eung Kweon; Adams, Hieab H H; Ikram, M Arfan; Zhu, Xiaofeng; Asselbergs, Folkert W; Kraaijeveld, Adriaan O; Beulens, Joline W J; Shu, Xiao-Ou; Rallidis, Loukianos S; Pedersen, Oluf; Hansen, Torben; Mitchell, Paul; Hewitt, Alex W; Kähönen, Mika; Pérusse, Louis; Bouchard, Claude; Tönjes, Anke; Chen, Yii-Der Ida; Pennell, Craig E; Mori, Trevor A; Lieb, Wolfgang; Franke, Andre; Ohlsson, Claes; Mellström, Dan; Cho, Yoon Shin; Lee, Hyejin; Yuan, Jian-Min; Koh, Woon-Puay; Rhee, Sang Youl; Woo, Jeong-Taek; Heid, Iris M; Stark, Klaus J; Zimmermann, Martina E; Völzke, Henry; Homuth, Georg; Evans, Michele K; Zonderman, Alan B; Polasek, Ozren; Pasterkamp, Gerard; Hoefer, Imo E; Redline, Susan; Pahkala, Katja; Oldehinkel, Albertine J; Snieder, Harold; Biino, Ginevra; Schmidt, Reinhold; Schmidt, Helena; Bandinelli, Stefania; Dedoussis, George; Thanaraj, Thangavel Alphonse; Kardia, Sharon L R; Peyser, Patricia A; Kato, Norihiro; Schulze, Matthias B; Girotto, Giorgia; Böger, Carsten A; Jung, Bettina; Joshi, Peter K; Bennett, David A; De Jager, Philip L; Lu, Xiangfeng; Mamakou, Vasiliki; Brown, Morris; Caulfield, Mark J; Munroe, Patricia B; Guo, Xiuqing; Ciullo, Marina; Jonas, Jost B; Samani, Nilesh J; Kaprio, Jaakko; Pajukanta, Päivi; Tusié-Luna, Teresa; Aguilar-Salinas, Carlos A; Adair, Linda S; Bechayda, Sonny Augustin; de Silva, H Janaka; Wickremasinghe, Ananda R; Krauss, Ronald M; Wu, Jer-Yuarn; Zheng, Wei; Hollander, Anneke Iden; Bharadwaj, Dwaipayan; Correa, Adolfo; Wilson, James G; Lind, Lars; Heng, Chew-Kiat; Nelson, Amanda E; Golightly, Yvonne M; Wilson, James F; Penninx, Brenda; Kim, Hyung-Lae; Attia, John; Scott, Rodney J; Rao, D C; Arnett, Donna K; Hunt, Steven C; Walker, Mark; Koistinen, Heikki A; Chandak, Giriraj R; Mercader, Josep M; Costanzo, Maria C; Jang, Dongkeun; Burtt, Noël P; Villalpando, Clicerio Gonzalez; Orozco, Lorena; Fornage, Myriam; Tai, EShyong; van Dam, Rob M; Lehtimäki, Terho; Chaturvedi, Nish; Yokota, Mitsuhiro; Liu, Jianjun; Reilly, Dermot F; McKnight, Amy Jayne; Kee, Frank; Jöckel, Karl-Heinz; McCarthy, Mark I; Palmer, Colin N A; Vitart, Veronique; Hayward, Caroline; Simonsick, Eleanor; van Duijn, Cornelia M; Jin, Zi-Bing; Qu, Jia; Hishigaki, Haretsugu; Lin, Xu; März, Winfried; Gudnason, Vilmundur; Tardif, Jean-Claude; Lettre, Guillaume; Hart, Leen M 't; Elders, Petra J M; Damrauer, Scott M; Kumari, Meena; Kivimaki, Mika; van der Harst, Pim; Spector, Tim D; Loos, Ruth J F; Province, Michael A; Parra, Esteban J; Cruz, Miguel; Psaty, Bruce M; Brandslund, Ivan; Pramstaller, Peter P; Rotimi, Charles N; Christensen, Kaare; Ripatti, Samuli; Widén, Elisabeth; Hakonarson, Hakon; Grant, Struan F A; Kiemeney, Lambertus A L M; de Graaf, Jacqueline; Loeffler, Markus; Kronenberg, Florian; Gu, Dongfeng; Erdmann, Jeanette; Schunkert, Heribert; Franks, Paul W; Linneberg, Allan; Jukema, J Wouter; Khera, Amit V; Männikkö, Minna; Jarvelin, Marjo-Riitta; Kutalik, Zoltan; Francesco, Cucca; Mook-Kanamori, Dennis O; van Dijk, Ko Willems; Watkins, Hugh; Strachan, David P; Grarup, Niels; Sever, Peter; Poulter, Neil; Chuang, Lee-Ming; Rotter, Jerome I; Dantoft, Thomas M; Karpe, Fredrik; Neville, Matt J; Timpson, Nicholas J; Cheng, Ching-Yu; Wong, Tien-Yin; Khor, Chiea Chuen; Li, Hengtong; Sabanayagam, Charumathi; Peters, Annette; Gieger, Christian; Hattersley, Andrew T; Pedersen, Nancy L; Magnusson, Patrik K E; Boomsma, Dorret I; Willemsen, Allegonda H M; Cupples, LAdrienne; van Meurs, Joyce B J; Ghanbari, Mohsen; Gordon-Larsen, Penny; Huang, Wei; Kim, Young Jin; Tabara, Yasuharu; Wareham, Nicholas J; Langenberg, Claudia; Zeggini, Eleftheria; Kuusisto, Johanna; Laakso, Markku; Ingelsson, Erik; Abecasis, Goncalo; Chambers, John C; Kooner, Jaspal S; de Vries, Paul S; Morrison, Alanna C; Hazelhurst, Scott; Ramsay, Michèle; North, Kari E; Daviglus, Martha; Kraft, Peter; Martin, Nicholas G; Whitfield, John B; Abbas, Shahid; Saleheen, Danish; Walters, Robin G; Holmes, Michael V; Black, Corri; Smith, Blair H; Baras, Aris; Justice, Anne E; Buring, Julie E; Ridker, Paul M; Chasman, Daniel I; Kooperberg, Charles; Tamiya, Gen; Yamamoto, Masayuki; van Heel, David A; Trembath, Richard C; Wei, Wei-Qi; Jarvik, Gail P; Namjou, Bahram; Hayes, M Geoffrey; Ritchie, Marylyn D; Jousilahti, Pekka; Salomaa, Veikko; Hveem, Kristian; Åsvold, Bjørn Olav; Kubo, Michiaki; Kamatani, Yoichiro; Okada, Yukinori; Murakami, Yoshinori; Kim, Bong-Jo; Thorsteinsdottir, Unnur; Stefansson, Kari; Zhang, Jifeng; Chen, YEugene; Ho, Yuk-Lam; Lynch, Julie A; Rader, Daniel J; Tsao, Philip S; Chang, Kyong-Mi; Cho, Kelly; O'Donnell, Christopher J; Gaziano, John M; Wilson, Peter W F; Frayling, Timothy M; Hirschhorn, Joel N; Kathiresan, Sekar; Mohlke, Karen L; Sun, Yan V; Morris, Andrew P; Boehnke, Michael; Brown, Christopher D; Natarajan, Pradeep; Deloukas, Panos; Willer, Cristen J; Assimes, Themistocles L; Peloso, Gina M (27.12.2022)
      article
      BACKGROUND: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding ...

    • Metabolic transition from childhood to adulthood based on two decades of biochemical time series in three longitudinal cohorts 

      Mäkinen, Ville Petteri; Kähönen, Mika; Lehtimäki, Terho; Hutri, Nina; Rönnemaa, Tapani; Viikari, Jorma; Pahkala, Katja; Rovio, Suvi; Niinikoski, Harri; Mykkänen, Juha; Raitakari, Olli; Ala-Korpela, Mika (2025)
      article
      BACKGROUND: This is the first large-scale longitudinal study of children that describes the temporal trajectories of an extensive collection of metabolic measures that are relevant for lifelong cardiometabolic risk. We ...

    • Randomized 20-year infancy-onset dietary intervention, life-long cardiovascular risk factors and retinal microvasculature 

      Repo, Oskari; Juonala, Markus; Niinikoski, Harri; Rovio, Suvi; Mykkänen, Juha; Lagström, Hanna; Cheung, Carol Y.; Yang, Dawei; Vaahtoranta-Lehtonen, Hanna; Jula, Antti; Nevalainen, Jaakko; Rönnemaa, Tapani; Viikari, Jorma; Raitakari, Olli; Tapp, Robyn; Pahkala, Katja (01.09.2024)
      article
      Background and Aims Retinal microvasculature characteristics predict cardiovascular morbidity and mortality. This study investigated associations of lifelong cardiovascular risk factors and effects of dietary intervention ...

    • Weekday and weekend physical activity patterns and their correlates among young adults 

      Suorsa, Kristin; Leskinen, Tuija; Rovio, Suvi; Niinikoski, Harri; Pentti, Jaana; Nevalainen, Jaakko; Heinonen, Olli J.; Lagström, Hanna; Jula, Antti; Viikari, Jorma; Rönnemaa, Tapani; Raitakari, Olli; Stenholm, Sari; Pahkala, Katja (08 / 2023)
      article
      Background: Accelerometers enable assessment of within and between day variation in physical activity. The main aim was to examine weekday and weekend physical activity patterns among young adults. Additionally, correlates ...

    • What is the role of puberty in the development of islet autoimmunity and progression to type 1 diabetes? 

      Peltonen, Essi J.; Veijola, Riitta; Ilonen, Jorma; Knip, Mikael; Niinikoski, Harri; Toppari, Jorma; Virtanen, Helena E; Virtanen, Suvi M; Peltonen, Jaakko; Nevalainen, Jaakko (20.04.2023)
      article
      <p>In many populations, the peak period of incidence of type 1 diabetes (T1D) has been observed to be around 10-14 years of age, coinciding with puberty, but direct evidence of the role of puberty in the development ...