"Myllykangas, Liisa" - Selaus tekijän mukaan TUNICRIS-julkaisut
-
Accumulation of Lewy-Related Pathology Starts in Middle Age: The Tampere Sudden Death Study
Kok, Eloise H.; Paetau, Anders; Martiskainen, Mika; Lyytikäinen, Leo Pekka; Lehtimäki, Terho; Karhunen, Pekka; Myllykangas, Liisa (05 / 2024)
articleWhen effective treatments against neurodegenerative diseases become a reality, it will be important to know the age these pathologies begin to develop. We investigated alpha-synuclein pathology in brain tissue of the Tampere ... -
COVID-19-infektion neurologiset ilmentymät
Laakso, Sini; Myllykangas, Liisa; Hietaharju, Aki (2021)
reviewarticle -
Distribution of Lewy-related pathology in the brain, spinal cord, and periphery: the population-based Vantaa 85 + study
Raunio, Anna; Kivistö, Ville; Kero, Mia; Tuimala, Jarno; Savola, Sara; Oinas, Minna; Kok, Eloise; Colangelo, Kia; Paetau, Anders; Polvikoski, Tuomo; Tienari, Pentti J; Puttonen, Henri; Myllykangas, Liisa (12.12.2022)
articleEvolving evidence has supported the existence of two anatomically distinct Lewy-related pathology (LRP) types. Investigation of spinal cord and peripheral LRP can elucidate mechanisms of Lewy body disorders and origins of ... -
Limbic-predominant age-related TDP-43 encephalopathy in the oldest old: a population-based study
Mikhailenko, Elizaveta; Colangelo, Kia; Tuimala, Jarno; Kero, Mia; Savola, Sara; Raunio, Anna; Kok, Eloise H; Tanskanen, Maarit; Mäkelä, Mira; Puttonen, Henri; Mäyränpää, Mikko I.; Kumar, Darshan; Kaivola, Karri; Paetau, Anders; Tienari, Pentti J; Polvikoski, Tuomo; Myllykangas, Liisa (01 / 2025)
articlePopulation-based cohort studies are essential for understanding the pathological basis of dementia in older populations. Previous studies have shown that limbic-predominant age-related TDP-43 encephalopathy neuropathologic ... -
Myocardial sympathetic distal axon loss in subjects with Lewy pathology in three autopsy cohorts
Kivistö, Ville; Englert, Benjamin; Tuimala, Jarno; Kok, Eloise; Puttonen, Henri; Raunio, Anna; Karhunen, Pekka J.; Lehtinen, Maria K.; Borghammer, Per; Ahvenainen, Ella; Colangelo, Kia; Savola, Sara; Tanskanen, Maarit; Kaivola, Karri; Tienari, Pentti J.; Kumar, Darshan; Paetau, Anders; Tynninen, Olli; Mäyränpää, Mikko I.; Polvikoski, Tuomo; Myllykangas, Liisa (2025)
articleCardiac manifestations are associated with Lewy body disease, but studies addressing the underlying histopathological mechanisms at the myocardial level are sparse. Here, we generated an artificial intelligence-based ... -
A postmortem study suggests a revision of the dual-hit hypothesis of Parkinson's disease
Borghammer, Per; Just, Mie Kristine; Horsager, Jacob; Skjærbæk, Casper; Raunio, Anna; Kok, Eloise H; Savola, Sara; Murayama, Shigeo; Saito, Yuko; Myllykangas, Liisa; Van Den Berge, Nathalie (30.11.2022)
articleThe dual-hit hypothesis of Parkinson's disease (PD) originally postulated that a neurotropic pathogen leads to formation of α-synuclein pathology in the olfactory bulb (OB) and dorsal motor nucleus of the vagus (DMV) and ...

