"Mykuliak, Vasyl V." - Selaus tekijän mukaan TUNICRIS-julkaisut
Viitteet 1-6 / 6
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Acetyl-NPKY of integrin-β1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity
(21.06.2024)
articleIntegrin-dependent crosstalk between cell-matrix adhesions and cell-cell junctions is critical for controlling endothelial permeability and proliferation in cancer and inflammatory diseases but remains poorly understood. ... -
Biochemical and structural characterization of beta-carbonic anhydrase from the parasite Trichomonas vaginalis
(2022)
articleAbstract: Trichomonas vaginalis is a unicellular parasite and responsible for one of the most common sexually transmittable infections worldwide, trichomoniasis. Carbonic anhydrases (CAs) are enzymes found in all lifeforms ... -
Cancer associated talin point mutations disorganise cell adhesion and migration
(2021)
articleTalin-1 is a key component of the multiprotein adhesion complexes which mediate cell migration, adhesion and integrin signalling and has been linked to cancer in several studies. We analysed talin-1 mutations reported in ... -
Microfluidics-Based Force Spectroscopy Enables High-Throughput Force Experiments with Sub-Nanometer Resolution and Sub-Piconewton Sensitivity
(2023)
articleSeveral techniques have been established to quantify the mechanicals of single molecules. However, most of them show only limited capabilities of parallelizing the measurement by performing many individual measurements ... -
Molecular dynamics simulations reveal how vinculin refolds partially unfolded talin rod helices to stabilize them against mechanical force
(08 / 2024)
articleVinculin binds to specific sites of mechanically unfolded talin rod domains to reinforce the coupling of the cell's exterior to its force generation machinery. Force-dependent vinculin- talin complexation and dissociation ...
