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    • HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies 

      Tedesco, Barbara; Vendredy, Leen; Adriaenssens, Elias; Cozzi, Marta; Asselbergh, Bob; Crippa, Valeria; Cristofani, Riccardo; Rusmini, Paola; Ferrari, Veronica; Casarotto, Elena; Chierichetti, Marta; Mina, Francesco; Pramaggiore, Paola; Galbiati, Mariarita; Piccolella, Margherita; Baets, Jonathan; Baeke, Femke; De Rycke, Riet; Mouly, Vincent; Laurenzi, Tommaso; Eberini, Ivano; Vihola, Anna; Udd, Bjarne; Weiss, Lan; Kimonis, Virginia; Timmerman, Vincent; Poletti, Angelo (2023)
      article
      Chaperone-assisted selective autophagy (CASA) is a highly selective pathway for the disposal of misfolding and aggregating proteins. In muscle, CASA assures muscle integrity by favoring the turnover of structural components ...