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    • Actin-microtubule cytoskeletal interplay mediated by MRTF-A/SRF signaling promotes dilated cardiomyopathy caused by LMNA mutations 

      Le Dour, Caroline; Chatzifrangkeskou, Maria; Macquart, Coline; Magiera, Maria M.; Peccate, Cécile; Jouve, Charlène; Virtanen, Laura; Heliö, Tiina; Aalto-Setälä, Katriina; Crasto, Silvia; Cadot, Bruno; Cardoso, Déborah; Mougenot, Nathalie; Adesse, Daniel; Di Pasquale, Elisa; Hulot, Jean Sébastien; Taimen, Pekka; Janke, Carsten; Muchir, Antoine (12 / 2022)
      article
      Mutations in the lamin A/C gene (LMNA) cause dilated cardiomyopathy associated with increased activity of ERK1/2 in the heart. We recently showed that ERK1/2 phosphorylates cofilin-1 on threonine 25 (phospho(T25)-cofilin-1) ...