"Laajala, Essi" - Selaus tekijän mukaan TUNICRIS-julkaisut

Viitteet 1-3 / 3

    • Early DNA methylation changes in children developing beta cell autoimmunity at a young age 

      Starskaia, Inna; Laajala, Essi; Grönroos, Toni; Härkönen, Taina; Junttila, Sini; Kattelus, Roosa; Kallionpää, Henna; Laiho, Asta; Suni, Veronika; Tillmann, Vallo; Lund, Riikka; Elo, Laura L.; Lähdesmäki, Harri; Knip, Mikael; Kalim, Ubaid Ullah; Lahesmaa, Riitta (2022)
      article
      Aims/hypothesis: Type 1 diabetes is a chronic autoimmune disease of complex aetiology, including a potential role for epigenetic regulation. Previous epigenomic studies focused mainly on clinically diagnosed individuals. ...

    • Permutation-based significance analysis reduces the type 1 error rate in bisulfite sequencing data analysis of human umbilical cord blood samples 

      Laajala, Essi; Halla-aho, Viivi; Grönroos, Toni; Kalim, Ubaid Ullah; Vähä-Mäkilä, Mari; Nurmio, Mirja; Kallionpää, Henna; Lietzén, Niina; Mykkänen, Juha; Rasool, Omid; Toppari, Jorma; Orešič, Matej; Knip, Mikael; Lund, Riikka; Lahesmaa, Riitta; Lähdesmäki, Harri (03 / 2022)
      article
      DNA methylation patterns are largely established in-utero and might mediate the impacts of in-utero conditions on later health outcomes. Associations between perinatal DNA methylation marks and pregnancy-related variables, ...

    • Umbilical cord blood DNA methylation in children who later develop type 1 diabetes 

      Laajala, Essi; Kalim, Ubaid Ullah; Grönroos, Toni; Rasool, Omid; Halla-aho, Viivi; Konki, Mikko; Kattelus, Roosa; Mykkänen, Juha; Nurmio, Mirja; Vähä-Mäkilä, Mari; Kallionpää, Henna; Lietzén, Niina; Ghimire, Bishwa R.; Laiho, Asta; Hyöty, Heikki; Elo, Laura L.; Ilonen, Jorma; Knip, Mikael; Lund, Riikka J.; Orešič, Matej; Veijola, Riitta; Lähdesmäki, Harri; Toppari, Jorma; Lahesmaa, Riitta (2022)
      article
      Aims/hypothesis: Distinct DNA methylation patterns have recently been observed to precede type 1 diabetes in whole blood collected from young children. Our aim was to determine whether perinatal DNA methylation is associated ...