"Koochakkhani, Shabnaz" - Selaus tekijän mukaan TUNICRIS-julkaisut

Viitteet 1-3 / 3

    • Design, synthesis and anticancer evaluation of novel arylhydrazones of active methylene compounds 

      Murugesan, Akshaya; Konda Mani, Saravanan; Koochakkhani, Shabnaz; Subramanian, Kumar; Kandhavelu, Jayalakshmi; Thiyagarajan, Ramesh; Gurbanov, Atash V.; Mahmudov, Kamran T.; Kandhavelu, Meenakshisundaram (01 / 2023)
      article
      Nerve growth factor (NGF) and its receptor, tropomyosin kinase receptor kinase type A (TrkA) is emerging as an important target for Glioblastoma (GBM) treatment. TrkA is the cancer biomarker majorly involved in tumor ...

    • Novel tetrahydroquinoline derivatives induce ROS-mediated apoptosis in glioblastoma cells 

      Koochakkhani, Shabnaz; Branco, Daniela S.N.; Alonso, Anxo Vila; Murugesan, Akshaya; Sarkar, Puja; Caires, Carina J.N.; Devanesan, Sandhanasamy; AlSalhi, Mohamad S.; Candeias, Nuno R.; Kandhavelu, Meenakshisundaram (01.09.2024)
      article
      Current treatment for Glioblastoma Multiforme (GBM) is not efficient due to its aggressive nature, tendency to infiltrate surrounding brain tissue, and chemotherapy resistance. Tetrahydroquinoline scaffolds are emerging ...

    • Preclinical validation of tetrahydroquinoline derivatives as EGFR inhibitor inducing glioblastoma cell death 

      Murugesan, Akshaya; Mani, Saravanan Konda; Smirnov, Aleksei; Koochakkhani, Shabnaz; Nambi Narayanan, Sabarish; Branco, Daniela S.N.; Devanesan, Sandhanasamy; Wadaan, Mohammad Ahmad; Candeias, Nuno R.; Kandhavelu, Meenakshisundaram (01.06.2026)
      article
      Glioblastoma multiforme, a malignant brain tumor has a dismal prognosis and lacks effective treatment. Epidermal growth factor receptor (EGFR) is an attractive drug target for GBM treatment, yet no therapeutic effect has ...