"Gulhan, Doga C" - Selaus tekijän mukaan TUNICRIS-julkaisut

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    • Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancer 

      Perez-Villatoro, Fernando; Oikkonen, Jaana; Casado, Julia; Chernenko, Anastasiya; Gulhan, Doga C; Tumiati, Manuela; Li, Yilin; Lavikka, Kari; Hietanen, Sakari; Hynninen, Johanna; Haltia, Ulla-Maija; Tyrmi, Jaakko S; Laivuori, Hannele; Konstantinopoulos, Panagiotis A; Hautaniemi, Sampsa; Kauppi, Liisa; Färkkilä, Anniina (29.12.2022)
      article
      Homologous recombination DNA-repair deficiency (HRD) is a common driver of genomic instability and confers a therapeutic vulnerability in cancer. The accurate detection of somatic allelic imbalances (AIs) has been limited ...