"Ercan, Selin" - Selaus tekijän mukaan TUNICRIS-julkaisut

Viitteet 1-15 / 15

    • Adult-Onset Compared to Childhood-Onset Asthma: Multifaceted Symptoms, Comorbidity, and Healthcare Burden 

      Abohalaka, Reshed; Ercan, Selin; Lehtimäki, Lauri; Lisik, Daniil; Ozuygur Ermis, Saliha Selin; Backman, Helena; Rådinger, Madeleine; Nwaru, Bright I.; Kankaanranta, Hannu (02 / 2026)
      letter
      In this study, we compared symptoms, comorbidities, and healthcare burden between childhood-onset asthma (< 18 years) and early adult-onset (18–39 years) and late adult-onset asthma (≥ 40 years). Among 3546 participants ...

    • Asthma Remission in Adults: Role of Age at Asthma Onset, Smoking, Obesity, and Allergic Rhinitis 

      Abohalaka, Reshed; Ercan, Selin; Lehtimäki, Lauri; Lisik, Daniil; Ozuygur Ermis, Saliha Selin; Ekerljung, Linda; Backman, Helena; Rådinger, Madeleine; Nwaru, Bright I.; Kankaanranta, Hannu (01 / 2025)
      letter

    • Blood eosinophil reference values and determinants in a representative adult population 

      Abohalaka, Reshed; Ercan, Selin; Lehtimäki, Lauri; Özuygur Ermis, Saliha Selin; Lisik, Daniil; Bashir Awad Bashir, Muwada; Jadhav, Radhika; Ekerljung, Linda; Wennergren, Göran; Lötvall, Jan; Pullerits, Teet; Backman, Helena; Rådinger, Madeleine; Nwaru, Bright I.; Kankaanranta, Hannu (05 / 2025)
      article
      Background: The use of blood eosinophil count (BEC) as a prognostic biomarker in the management of conditions such as asthma and chronic obstructive pulmonary disease (COPD) may be complicated by factors such as atopy, ...

    • Characteristics of Adult Asthma Based on Type 2 Inflammation Markers: A Population-Based Study 

      Ercan, Selin; Abohalaka, Reshed; Ilmarinen, Pinja; Lehtimäki, Lauri; Ermis, Saliha Selin Ozuygur; Lisik, Daniil; Bashir, Muwada Bashir Awad; Jadhav, Radhika; Vähätalo, Iida; Malmhäll, Carina; Backman, Helena; Wennergren, Göran; Ekerljung, Linda; Lötvall, Jan; Pullerits, Teet; Rådinger, Madeleine; Nwaru, Bright I.; Kankaanranta, Hannu (2025)
      article
      Background: The “type 2 (T2)-high” phenotype has a relatively well-defined pathophysiology compared with “T2-low” asthma. T2-low asthma has been mostly studied among severe asthma cases. Objective: To estimate the proportion ...

    • Fractional exhaled nitric oxide and blood eosinophils in relation to lung function, allergy and nasal polyps in asthma 

      Abohalaka, Reshed; Lehtimäki, Lauri; Ercan, Selin; Lisik, Daniil; Özuygur Ermis, Saliha Selin; Ilmarinen, Pinja; Pullerits, Teet; Backman, Helena; Rådinger, Madeleine; Nwaru, Bright I.; Kankaanranta, Hannu (09 / 2026)
      article
      Background: Type 2 inflammation plays a central role in asthma, but blood eosinophil count (BEC) and fractional exhaled nitric oxide (FENO) levels may reflect different type 2 pathways. Their associations with different ...

    • Late-Onset Asthma Phenotypes by Onset Age: A Cluster Analysis in Swedish Population-Based Cohorts 

      Lisik, Daniil; Backman, Helena; Basna, Rani; Hedman, Linnea; Bashir, Muwada Bashir Awad; Ercan, Selin; Abohalaka, Reshed; Ermis, Saliha Selin Özuygur; Ekerljung, Linda; Stridsman, Caroline; Winsa-Lindmark, Sofia; Mincheva, Roxana; Pullerits, Teet; Lötvall, Jan; Lindberg, Anne; Rådinger, Madeleine; Rönmark, Eva; Kankaanranta, Hannu; Nwaru, Bright I. (12 / 2025)
      letter

    • Lifetime asthma incidence is related to age at onset and allergies in western Sweden 

      Abohalaka, Reshed; Ercan, Selin; Lehtimäki, Lauri; Ekerljung, Linda; Backman, Helena; Uslu, Fatma Zehra; Ermis, Saliha Selin Ozuygur; Rådinger, Madeleine; Nwaru, Bright I.; Kankaanranta, Hannu (12 / 2024)
      reviewarticle
      Although asthma is more frequently diagnosed in childhood, a substantial proportion of cases manifests in adulthood. Nonetheless, few studies have comprehensively examined asthma incidence across different ages, genders, ...

    • Machine learning-derived asthma and allergy trajectories in children: a systematic review and meta-analysis 

      Lisik, Daniil; Özuygur Ermis, Saliha Selin; Milani, Gregorio Paolo; Spolidoro, Giulia Carla Immacolata; Ercan, Selin; Salisu, Michael; Odetola, Faozyat; Ghiglioni, Daniele Giovanni; Pylov, Danylo; Goksör, Emma; Basna, Rani; Wennergren, Göran; Kankaanranta, Hannu; Nwaru, Bright I. (2025)
      article
      INTRODUCTION: Numerous studies have characterised trajectories of asthma and allergy in children using machine learning, but with different techniques and mixed findings. The present work aimed to summarise the evidence ...

    • Obesity and weight change during eight years in relation to asthma incidence 

      Abohalaka, Reshed; Ercan, Selin; Ilmarinen, Pinja; Backman, Helena; Ekerljung, Linda; Rådinger, Madeleine; Nwaru, Bright I.; Kankaanranta, Hannu (10 / 2025)
      article
      Obesity has been associated with increased prevalence of asthma in cross-sectional studies. We aim to examine the relation of obesity and weight change to 8-year asthma incidence in a randomly selected population-based ...

    • Reference Values and Determinants of Fractional Exhaled Nitric Oxide in a Representative Adult Population in Western Sweden 

      Abohalaka, Reshed; Ercan, Selin; Lehtimäki, Lauri; Özuygur Ermis, Saliha Selin; Lisik, Daniil; Bashir Awad Bashir, Muwada; Jadhav, Radhika; Ekerljung, Linda; Wennergren, Göran; Lötvall, Jan; Pullerits, Teet; Backman, Helena; Rådinger, Madeleine; Nwaru, Bright I.; Kankaanranta, Hannu (09 / 2025)
      article
      Background: Fractional exhaled nitric oxide (FENO) is used to differentiate asthma inflammatory phenotypes and guide its management. However, data on FENO reference values in a representative adult population is limited. ...

    • Serum and nasal lavage fluid eosinophil-derived neurotoxin levels and their determinants in adults 

      Özuygur Ermis, Saliha Selin; Malmhäll, Carina; Borres, Magnus P.; Movérare, Robert; Lisik, Daniil; Abohalaka, Reshed; Ercan, Selin; Schmeisser, Susanne; Basna, Rani; Mincheva, Roxana; Wennergren, Göran; Lötvall, Jan; Ekerljung, Linda; Rådinger, Madeleine; Kankaanranta, Hannu; Nwaru, Bright I. (08 / 2025)
      article
      Background: Eosinophil-derived neurotoxin (EDN), an eosinophil granule protein, is a candidate biomarker in asthma to reflect eosinophilic activation. Objective: We sought to characterize the distribution of serum and nasal ...

    • Serum and Nasal Lavage Fluid Eosinophil-Derived Neurotoxin Levels in Clinically Defined Asthma Phenotypes 

      Özuygur Ermis, Saliha Selin; Malmhäll, Carina; Borres, Magnus P.; Movérare, Robert; Lisik, Daniil; Abohalaka, Reshed; Ercan, Selin; Schmeisser, Susanne; Basna, Rani; Mincheva, Roxana; Wennergren, Göran; Lötvall, Jan; Ekerljung, Linda; Rådinger, Madeleine; Kankaanranta, Hannu; Nwaru, Bright I. (06 / 2026)
      article
      Background: As a surrogate for eosinophilic activation, eosinophil-derived neurotoxin (EDN) is a potential clinical biomarker. However, EDN levels and discriminatory ability in different asthma phenotypes are unknown. We ...

    • Sex steroid hormones and asthma in males: a state-of-the-art review 

      Ozuygur Ermis, Saliha Selin; Ercan, Selin; Malmhäll, Carina; Adesoba, Helen; Salisu, Michael; Bossios, Apostolos; Rådinger, Madeleine; Kankaanranta, Hannu; Nwaru, Bright I. (12.05.2025)
      reviewarticle
      Introduction: The incidence, prevalence, and disease prognosis of asthma differ between males and females throughout the life course. However, the underlying mechanisms are not known. Sex hormones might have a potential ...

    • Stability of Type 2 Inflammation in a 12-Year Adult-Onset Asthma Follow-Up Study 

      Flinkman, Ella; Vähätalo, Iida; Tuomisto, Leena E.; Lehtimäki, Lauri; Niemelä, Onni; Rådinger, Madeleine; Nwaru, Bright I.; Ercan, Selin; Hämäläinen, Mari; Moilanen, Eeva; Ilmarinen, Pinja; Kankaanranta, Hannu (2026)
      article
      Purpose: To assess the stability of T2 inflammation and clinical features associated with high or low T2 markers in adult-onset asthma. Patients and Methods: Seinäjoki Adult Asthma Study is a 12-year follow-up study including ...

    • Unsupervised Machine Learning Identifies Asthma Phenotypes in the Population-Based West Sweden Asthma Study 

      Bashir, Muwada Bashir Awad; Lisik, Daniil; Ermis, Saliha Selin Ozuygur; Basna, Rani; Abohalaka, Reshed; Ercan, Selin; Backman, Helena; Pullerits, Teet; Mincheva, Roxana; Wennergren, Göran; Rådinger, Madeleine; Lötvall, Jan; Ekerljung, Linda; Kankaanranta, Hannu; Nwaru, Bright I. (02 / 2025)
      letter