"Delgado, Graciela E." - Selaus tekijän mukaan TUNICRIS-julkaisut

Viitteet 1-7 / 7

    • Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus 

      Tin, Adrienne; Schlosser, Pascal; Matias-Garcia, Pamela R.; Thio, Chris H.L.; Joehanes, Roby; Liu, Hongbo; Yu, Zhi; Weihs, Antoine; Hoppmann, Anselm; Grundner-Culemann, Franziska; Min, Josine L.; Kuhns, Victoria L.Halperin; Adeyemo, Adebowale A.; Agyemang, Charles; Ärnlöv, Johan; Aziz, Nasir A.; Baccarelli, Andrea; Bochud, Murielle; Brenner, Hermann; Bressler, Jan; Breteler, Monique M.B.; Carmeli, Cristian; Chaker, Layal; Coresh, Josef; Corre, Tanguy; Correa, Adolfo; Cox, Simon R.; Delgado, Graciela E.; Eckardt, Kai Uwe; Ekici, Arif B.; Endlich, Karlhans; Floyd, James S.; Fraszczyk, Eliza; Gao, Xu; Gào, Xīn; Gelber, Allan C.; Ghanbari, Mohsen; Ghasemi, Sahar; Gieger, Christian; Greenland, Philip; Grove, Megan L.; Harris, Sarah E.; Hemani, Gibran; Henneman, Peter; Herder, Christian; Horvath, Steve; Hou, Lifang; Hurme, Mikko A.; Lehtimäki, Terho; Mishra, Pashupati P. (12 / 2021)
      article
      Elevated serum urate levels, a complex trait and major risk factor for incident gout, are correlated with cardiometabolic traits via incompletely understood mechanisms. DNA methylation in whole blood captures genetic and ...

    • Genetic risk score for coronary artery calcification and its predictive ability for coronary artery disease 

      Mishra, Pashupati P.; Mishra, Binisha H.; Lyytikäinen, Leo Pekka; Goebeler, Sirkka; Martiskainen, Mika; Hakamaa, Emma; Kleber, Marcus E.; Delgado, Graciela E.; März, Winfried; Kähönen, Mika; Karhunen, Pekka J.; Lehtimäki, Terho (12 / 2024)
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      Aim: The modest added predictive value of the existing genetic risk scores (GRSs) for coronary artery disease (CAD) could be partly due to missing genetic components, hidden in the genetic architecture of intermediate ...

    • Genome-wide analysis identifies novel susceptibility loci for myocardial infarction 

      Hartiala, Jaana A.; Han, Yi; Jia, Qiong; Hilser, James R.; Huang, Pin; Gukasyan, Janet; Schwartzman, William S.; Cai, Zhiheng; Biswas, Subarna; Trégouët, David Alexandre; Smith, Nicholas L.; Seldin, Marcus; Pan, Calvin; Mehrabian, Margarete; Lusis, Aldons J.; Bazeley, Peter; Sun, Yan V.; Liu, Chang; Quyyumi, Arshed A.; Scholz, Markus; Thiery, Joachim; Delgado, Graciela E.; Kleber, Marcus E.; März, Winfried; Howe, Laurence J.; Asselbergs, Folkert W.; van Vugt, Marion; Vlachojannis, Georgios J.; Patel, Riyaz S.; Lyytikäinen, Leo Pekka; Kähönen, Mika; Lehtimäki, Terho; Nieminen, Tuomo V.M.; Kuukasjärvi, Pekka; Laurikka, Jari O.; Chang, Xuling; Heng, Chew Kiat; Jiang, Rong; Kraus, William E.; Hauser, Elizabeth R.; Ferguson, Jane F.; Reilly, Muredach P.; Ito, Kaoru; Koyama, Satoshi; Kamatani, Yoichiro; Komuro, Issei; Stolze, Lindsey K.; Romanoski, Casey E.; Khan, Mohammad Daud; Turner, Adam W. (2021)
      article
      AIMS: While most patients with myocardial infarction (MI) have underlying coronary atherosclerosis, not all patients with coronary artery disease (CAD) develop MI. We sought to address the hypothesis that some of the genetic ...

    • A genome-wide association meta-analysis of cholesterol synthesis intermediates identifies three associations for lanosterol 

      Förster, Franz; Horn, Katrin; Pott, Janne; Delgado, Graciela E.; Kleber, Marcus E.; März, Winfried; Moissl-Blanke, Angela Patricia; Silbernagel, Günther; Waldenberger, Melanie; Grallert, Harald; Peters, Annette; Gieger, Christian; Baber, Ronny; Kirsten, Holger; Loeffler, Markus; Isermann, Berend; Thiery, Joachim; Kovacs, Peter; Tönjes, Anke; Stumvoll, Michael; Gylling, Helena; Kähönen, Mika; Lehtimäki, Terho; Mishra, Pashupati Prasad; Raitakari, Olli; Ceglarek, Uta; Scholz, Markus (02 / 2026)
      article
      Background: Cholesterol is a main contributor to coronary artery disease (CAD). Although the genetic basis of blood cholesterol concentration is well studied, there is currently a lack of studies investigating the genetics ...

    • Genome-wide association study of circulating interleukin 6 levels identifies novel loci 

      -, -; Ahluwalia, Tarunveer S.; Prins, Bram P.; Abdollahi, Mohammadreza; Armstrong, Nicola J.; Aslibekyan, Stella; Bain, Lisa; Jefferis, Barbara; Baumert, Jens; Beekman, Marian; Ben-Shlomo, Yoav; Bis, Joshua C.; Mitchell, Braxton D.; de Geus, Eco; Delgado, Graciela E.; Marek, Diana; Eriksson, Joel; Kajantie, Eero; Kanoni, Stavroula; Kemp, John P.; Lu, Chen; Marioni, Riccardo E.; McLachlan, Stela; Milaneschi, Yuri; Nolte, Ilja M.; Petrelis, Alexandros M.; Porcu, Eleonora; Sabater-Lleal, Maria; Naderi, Elnaz; Seppälä, Ilkka; Shah, Tina; Singhal, Gaurav; Standl, Marie; Teumer, Alexander; Thalamuthu, Anbupalam; Thiering, Elisabeth; Trompet, Stella; Ballantyne, Christie M.; Benjamin, Emelia J.; Casas, Juan P.; Toben, Catherine; Dedoussis, George; Deelen, Joris; Durda, Peter; Engmann, Jorgen; Feitosa, Mary F.; Grallert, Harald; Hammarstedt, Ann; Lahti, Jari; Eriksson, Johan G.; Lehtimäki, Terho (2021)
      article
      <p>Interleukin 6 (IL-6) is a multifunctional cytokine with both pro- and anti-inflammatory properties with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been associated with an ...

    • High genetic risk for depression as an independent risk factor for mortality in patients referred for coronary angiography 

      Krämer, Robert M.; Moissl, Angela P.; Lorkowski, Stefan; Krämer, Bernhard K.; Lehtimäki, Terho; Mishra, Binisha H.; Mishra, Pashupati P.; Leipe, Jan; März, Winfried; Kleber, Marcus E.; Müller-Myhsok, Bertram; Delgado, Graciela E. (2023)
      article
      <p>Background: Different observations have suggested that patients with depression have a higher risk for a number of comorbidities and mortality. The underlying causes have not been fully understood yet. Aims: The ...

    • Meta-analyses identify DNA methylation associated with kidney function and damage 

      Schlosser, Pascal; Tin, Adrienne; Matias-Garcia, Pamela R.; Thio, Chris H.L.; Joehanes, Roby; Liu, Hongbo; Weihs, Antoine; Yu, Zhi; Hoppmann, Anselm; Grundner-Culemann, Franziska; Min, Josine L.; Adeyemo, Adebowale A.; Agyemang, Charles; Ärnlöv, Johan; Aziz, Nasir A.; Baccarelli, Andrea; Bochud, Murielle; Brenner, Hermann; Breteler, Monique M.B.; Carmeli, Cristian; Chaker, Layal; Chambers, John C.; Cole, Shelley A.; Coresh, Josef; Corre, Tanguy; Correa, Adolfo; Cox, Simon R.; de Klein, Niek; Delgado, Graciela E.; Domingo-Relloso, Arce; Eckardt, Kai Uwe; Ekici, Arif B.; Endlich, Karlhans; Evans, Kathryn L.; Floyd, James S.; Fornage, Myriam; Franke, Lude; Fraszczyk, Eliza; Gao, Xu; Gào, Xīn; Ghanbari, Mohsen; Ghasemi, Sahar; Gieger, Christian; Greenland, Philip; Grove, Megan L.; Harris, Sarah E.; Hemani, Gibran; Hurme, Mikko A.; Lehtimäki, Terho; Mishra, Pashupati P. (12 / 2021)
      article
      Chronic kidney disease is a major public health burden. Elevated urinary albumin-to-creatinine ratio is a measure of kidney damage, and used to diagnose and stage chronic kidney disease. To extend the knowledge on regulatory ...