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Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis

Ceric, Ameldina; Holgersson, Johan; May, Teresa L.; Skrifvars, Markus B.; Hästbacka, Johanna; Saxena, Manoj; Aneman, Anders; Delaney, Anthony; Reade, Michael C.; Delcourt, Candice; Jakobsen, Janus Christian; Nielsen, Niklas (05 / 2024)
article

Background: Sedation is routinely administered to critically ill patients to alleviate anxiety, discomfort, and patient-ventilator asynchrony. However, it must be balanced against risks such as delirium and prolonged ...