"Debacq-Chainiaux, Florence" - Selaus tekijän mukaan TUNICRIS-julkaisut

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    • Association between bilirubin and biomarkers of metabolic health and oxidative stress in the MARK-AGE cohort 

      Schoissengeier, Vanessa; Maqboul, Lina; Weber, Daniela; Grune, Tilman; Bürkle, Alexander; Moreno-Villaneuva, Maria; Franceschi, Claudio; Capri, Miriam; Bernhard, Jürgen; Toussaint, Olivier; Debacq-Chainiaux, Florence; Weinberger, Birgit; Gonos, Efstathios S.; Sikora, Ewa; Dollé, Martijn; Jansen, Eugène; Slagboom, P. Eline; Hervonen, Antti; Hurme, Mikko; Breusing, Nicolle; Frank, Jan; Bulmer, Andrew C.; Wagner, Karl Heinz (19.07.2024)
      article
      Recent studies have shown that elevated concentrations of unconjugated bilirubin (UCB) may be a protective host factor against the development of noncommunicable diseases (NCDs), whereas low levels of UCB are associated ...

    • Association Between TTV Viremia, Chronic Inflammation, and Ischemic Heart Disease Risk: Insights From MARK-AGE and Report-Age Projects 

      Giacconi, Robertina; Piacenza, Francesco; Maggi, Fabrizio; Bürkle, Alexander; Moreno-Villanueva, María; Mancinelli, Lucia; Spezia, Pietro Giorgio; Novazzi, Federica; Ferrante, Francesca Drago; Minosse, Claudia; Grossi, Paolo Antonio; Mancini, Nicasio; Cecati, Monia; Dollé, Martijn E.T.; Jansen, Eugène; Grune, Tilman; Gonos, Efstathios S.; Franceschi, Claudio; Capri, Miriam; Weinberger, Birgit; Sikora, Ewa; Debacq-Chainiaux, Florence; Stuetz, Wolfgang; Hurme, Mikko; Eline Slagboom, P.; Bernhardt, Jürgen; Gentilini, Davide; Calzari, Luciano; Di Rosa, Mirko; Bonfigli, Anna Rita; Galeazzi, Roberta; Cherubini, Antonio; Lattanzio, Fabrizia; Provinciali, Mauro; Malavolta, Marco (11 / 2024)
      article
      The implication of Torquetenovirus (TTV) in ischemic heart disease (IHD) has not been thoroughly explored. This study investigated the association between TTV viremia, pro-inflammatory cytokines, and IHD risk in an aging ...

    • Associations of circulating GDF15 with combined cognitive frailty and depression in older adults of the MARK-AGE study 

      Kochlik, Bastian; Herpich, Catrin; Moreno-Villanueva, María; Klaus, Susanne; Müller-Werdan, Ursula; Weinberger, Birgit; Fiegl, Simone; Toussaint, Olivier; Debacq-Chainiaux, Florence; Schön, Christiane; Bernhardt, Jürgen; Breusing, Nicolle; Gonos, Efstathios S.; Franceschi, Claudio; Capri, Miriam; Sikora, Ewa; Hervonen, Antti; Hurme, Mikko; Slagboom, P. Eline; Dollé, Martijn E.T.; Jansen, Eugene; Grune, Tilman; Bürkle, Alexander; Norman, Kristina (04 / 2023)
      article
      Growth differentiation factor-15 (GDF15) might be involved in the development of cognitive frailty and depression. Therefore, we evaluated cross-sectional associations of plasma GDF15 with combined cognitive-frailty-and-depression ...

    • Bacterial DNAemia in older subjects and nonagenarian offspring and association with redox biomarkers: results from MARK-AGE Study 

      Giacconi, Robertina; D'Aquila, Patrizia; Malavolta, Marco; Piacenza, Francesco; Bürkle, Alexander; Moreno Villanueva, María; Dollé, Martijn E T; Jansen, Eugène; Grune, Tilman; Gonos, Efstathios S; Franceschi, Claudio; Capri, Miriam; Gradinaru, Daniela; Grubeck-Loebenstein, Beatrix; Sikora, Ewa; Stuetz, Wolfgang; Weber, Daniela; Toussaint, Olivier; Debacq-Chainiaux, Florence; Hervonen, Antti; Hurme, Mikko; Slagboom, P Eline; Schön, Christiane; Bernhardt, Jürgen; Breusing, Nicolle; Duncan, Talbot; Passarino, Giuseppe; Bellizzi, Dina; Provinciali, Mauro (02.08.2022)
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    • Biologically Younger Individuals, as Identified by MARK-AGE Biological Age Scores, Display a Distinct Favourable Blood Chemistry Profile Regardless of Age 

      Moreno-Villanueva, María; Junk, Michael; Mosieniak, Grażyna; Sikora, Ewa; Capri, Miriam; Garagnani, Paolo; Pirazzini, Chiara; Breusing, Nicolle; Bernhardt, Jürgen; Schön, Christiane; Blasco, María; Zondag, Gerben; Debacq-Chainiaux, Florence; Grubeck-Loebenstein, Beatrix; Weinberger, Birgit; Fiegl, Simone; Mocchegiani, Eugenio; Malavolta, Marco; Giacconi, Robertina; Piacenza, Francesco; Collino, Sebastiano; Gonos, Efstathios S.; Gradinaru, Daniela; Dollé, Martijn E.T.; Jansen, Eugène; Salmon, Michel; Kristensen, Peter; Griffiths, Helen; Libert, Claude; Vanhooren, Valerie; Simm, Andreas; Talbot, Duncan; Caiafa, Paola; Bacalini, Maria Giulia; Zampieri, Michele; Friguet, Bertrand; Petropoulos, Isabelle; Slagboom, P. Eline; Westendorp, Rudi; Hervonnen, Antti; Hurme, Mikko; Aspinall, Richard; Govind, Sheila; Weber, Daniela; Stuetz, Wolfgang; Hoeijmakers, Jan H.J.; Gavriushina, Iuliia; Sampson, Oliver R.; Castellani, Gastone; Berthold, Michael R.; Grune, Tilman; Franceschi, Claudio; Bürkle, Alexander (03 / 2026)
      article
      Biomarkers of ageing are defined as age-related changes in body function or composition that could serve as a measure of ‘biological’ age and predict the onset of age-related diseases and/or residual life expectancy. We ...

    • Circulating cell-free DNA in health and disease: the relationship to health behaviours, ageing phenotypes and metabolomics 

      Kananen, Laura; Hurme, Mikko; Bürkle, Alexander; Moreno-Villanueva, Maria; Bernhardt, Jürgen; Debacq-Chainiaux, Florence; Grubeck-Loebenstein, Beatrix; Malavolta, Marco; Basso, Andrea; Piacenza, Francesco; Collino, Sebastiano; Gonos, Efstathios S.; Sikora, Ewa; Gradinaru, Daniela; Jansen, Eugene H.J.M.; Dollé, Martijn E.T.; Salmon, Michel; Stuetz, Wolfgang; Weber, Daniela; Grune, Tilman; Breusing, Nicolle; Simm, Andreas; Capri, Miriam; Franceschi, Claudio; Slagboom, Eline; Talbot, Duncan; Libert, Claude; Raitanen, Jani; Koskinen, Seppo; Härkänen, Tommi; Stenholm, Sari; Ala-Korpela, Mika; Lehtimäki, Terho; Raitakari, Olli T.; Ukkola, Olavi; Kähönen, Mika; Jylhä, Marja; Jylhävä, Juulia (2022)
      article
      Circulating cell-free DNA (cf-DNA) has emerged as a promising biomarker of ageing, tissue damage and cellular stress. However, less is known about health behaviours, ageing phenotypes and metabolic processes that lead to ...

    • Microbiome in Blood Samples From the General Population Recruited in the MARK-AGE Project: A Pilot Study 

      D’Aquila, Patrizia; Giacconi, Robertina; Malavolta, Marco; Piacenza, Francesco; Bürkle, Alexander; Villanueva, María Moreno; Dollé, Martijn E.T.; Jansen, Eugène; Grune, Tilman; Gonos, Efstathios S.; Franceschi, Claudio; Capri, Miriam; Grubeck-Loebenstein, Beatrix; Sikora, Ewa; Toussaint, Olivier; Debacq-Chainiaux, Florence; Hervonen, Antti; Hurme, Mikko; Slagboom, P. Eline; Schön, Christiane; Bernhardt, Jürgen; Breusing, Nicolle; Passarino, Giuseppe; Provinciali, Mauro; Bellizzi, Dina (2021)
      article
      The presence of circulating microbiome in blood has been reported in both physiological and pathological conditions, although its origins, identities and function remain to be elucidated. This study aimed to investigate ...

    • TTV Species Diversity as a Novel Biomarker of Immune Dysregulation in Aging 

      Novazzi, Federica; Spezia, Pietro Giorgio; Ferrante, Francesca Drago; Genoni, Angelo Paolo; Grossi, Paolo Antonio; Mancini, Nicasio; Malavolta, Marco; Ballietti, Marta; Piacenza, Francesco; Marcozzi, Serena; Fortunato, Carlo; Badillo Pazmay, Gretta Veronica; Cianfruglia, Laura; Bürkle, Alexander; Moreno-Villanueva, María; Dollé, Martijn E.T.; Jansen, Eugène; Grune, Tilman; Gonos, Efstathios S.; Franceschi, Claudio; Capri, Miriam; Zampieri, Michele; Caiafa, Paola; Ciccarone, Fabio; Reale, Anna; Weinberger, Birgit; Sikora, Ewa; Debacq-Chainiaux, Florence; Stuetz, Wolfgang; Hurme, Mikko; Slagboom, P. Eline; Bernhardt, Jürgen; Olivieri, Fabiola; Filippini, Fabio; Maggi, Fabrizio; Giacconi, Robertina (11 / 2025)
      article
      Torquetenovirus (TTV) is a prevalent virus whose clinical significance remains unclear, potentially linked to immunosenescence. This study examines TTV species in relation to immune impairment, inflammation, and cellular ...