"Aalto-Setälä, K" - Selaus tekijän mukaan TUNICRIS-julkaisut
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Automatic optimization of an in silico model of human iPSC derived cardiomyocytes recapitulating calcium handling abnormalities
Paci, M; Pölönen, RP; Cori, D; Penttinen, K.; Aalto-Setälä, K; Severi, S.; Hyttinen, J. (2018)
articleThe growing importance of human induced pluripotent stem cell-derived cardiomyoyctes (hiPSC-CMs), as patient-specific and disease-specific models for studying cellular cardiac electrophysiology or for preliminary cardiotoxicity ... -
Microelectrode array for noninvasive analysis of cardiomyocytes at the single-cell level
Rynänen, T; Pekka-Mattila, M; Shah, D; Kreutzer, J.; Kallio, P.; Lekkala, Jukka; Aalto-Setälä, K (2018)
articleMicroelectrode arrays (MEAs) are widely used to assess the electrophysiology of human pluripotent stem cell-derived cardiomyocytes (hPS-CMs). Traditionally, MEAs have been used to record data at the cell population level, ... -
Polyethylene Terephthalate Textiles Enhance the Structural Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Pekkanen-Mattila, Mari; Häkli, M; Pölönen, R; Mansikkala, T; Junnila, Anni; Talvitie, E; Koivisto, JT; Kellomäki, M; Aalto-Setälä, K (2019)
articleHuman-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have the potential to serve as a model for human cardiomyocytes. However, hiPSC-CMs are still considered immature. CMs differentiated from hiPSCs more ... -
A Portable Microscale Cell Culture System with Indirect Temperature Control
Mäki, A; Verho, J; Kreutzer, J; Ryynänen, T.; Rajan, D.; Pekkanen-Mattila, Mari; Ahola, A.; Hyttinen, J.; Aalto-Setälä, K; Lekkala, Jukka; Kallio, P. (2018)
articleA physiologically relevant environment is essential for successful long-term cell culturing in vitro. Precise control of temperature, one of the most crucial environmental parameters in cell cultures, increases the fidelity ...