"Österlund, Pia" - Selaus tekijän mukaan TUNICRIS-julkaisut
Viitteet 1-16 / 16
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Association between Computed Tomography-Determined Loss of Muscle Mass and Impaired Three-Month Survival in Frail Older Adults with Cancer
(06 / 2023)
article<p>As patients with solid (non-hematological) cancers and a life expectancy of <3 months rarely benefit from oncological treatment, we examined whether the CT-determined loss of muscle mass is associated with an impaired ... -
Atypical (non-V600E) BRAF mutations in metastatic colorectal cancer in population and real-world cohorts
(02 / 2023)
article<p>BRAF-V600E mutation (mt) is a strong negative prognostic and predictive biomarker in metastatic colorectal cancer (mCRC). Non-V600Emt, designated atypical BRAFmt (aBRAFmt) are rare, and little is known about their ... -
Computed tomography-determined high visceral adipose tissue and sarcopenic obesity and their associations with survival in vulnerable or frail older adults with cancer considered for systemic anticancer treatment
(14.03.2024)
article<p>Introduction: Treatment decisions are challenging in older adults with solid tumors. Geriatric 8 (G8)-screening and comprehensive geriatric assessment (CGA) are important but additional methods are needed. We examined ... -
Detailed analysis of metastatic colorectal cancer patients who developed cardiotoxicity on another fluoropyrimidine and switched to S-1 treatment (subgroup analysis of the CardioSwitch-study)
(02.05.2024)
article<p>BACKGROUND AND PURPOSE: The CardioSwitch-study demonstrated that patients with solid tumors who develop cardiotoxicity on capecitabine or 5-fluorouracil (5-FU) treatment can be safely switched to S-1, an alternative ... -
Geriatrinen arviointi ohjaa iäkkään syöpäpotilaan hoidon suunnittelua
(01.09.2023)
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Geriatriset oireyhtymät ovat yleisiä iäkkäillä syöpäpotilailla
(09 / 2022)
articleBackground Age increases the risk of cancer and ageing processes affect treatment decisions. The aim of this study was to recognize geriatric syndromes and to evaluate the G8 screening tool for identifying patients who ... -
KRAS-G12C Mutation in One Real-Life and Three Population-Based Nordic Cohorts of Metastatic Colorectal Cancer
(16.02.2022)
article<p>Background: KRAS mutations, present in over 40% of metastatic colorectal cancer (mCRC), are negative predictive factors for anti-EGFR therapy. Mutations in KRAS-G12C have a cysteine residue for which drugs have been ... -
Metastatic Rectal Carcinoma with Long-Term Remission due to Modern Multimodality Treatment
(2021)
article<p>In the era of personalized medicine, systemic treatment with chemotherapy in combination with targeted drugs, tailored according to RAS and BRAF status, has improved the survival of patients with metastatic colorectal ... -
PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3
(2020)
article<p>Gastroenteropancreatic neuroendocrine neoplasms grade 3 (GEP-NENs G3) are rare tumors. These highly aggressive neoplasms are traditionally treated with platinum-based chemotherapy in combination with etoposide. Immune ... -
Quality of Life in Vulnerable Older Patients with Metastatic Colorectal Cancer Receiving Palliative Chemotherapy: The Randomized NORDIC9-Study
(2021)
article<p>Quality of life data from randomized trials are lacking in older patients with metastatic colorectal cancer (mCRC). In the randomized NORDIC9-study, reduced-dose S1+oxaliplatin (SOx) showed superior efficacy compared ... -
Repeated centralized multidisciplinary team assessment of resectability, clinical behaviour, and outcomes in 1086 Finnish metastatic colorectal cancer patients (RAXO): a nationwide prospective intervention study
(2021)
articleBackground Resection of colorectal cancer (CRC) metastases provides good survival but is probably underused in real-world practice. Methods A prospective Finnish nationwide study enrolled treatable metastatic CRC patients. ... -
Sex hormones and sperm parameters after adjuvant oxaliplatin-based treatment for colorectal cancer
(01 / 2022)
article<p>Background: The incidence of colorectal cancer (CRC) in individuals of fertile age is increasing. Oxaliplatin is a cornerstone treatment in the adjuvant setting for stage III and high-risk stage II CRC. Limited data ... -
Time to act!: - A cross-sectional study on how nutritional risk increases during hospitalization and associates with worse outcome
(10 / 2023)
article<p>Background & aims: Nutritional risk is prevalent, and it develops negatively during hospital stay. The aim of this cohort study was to assess the association of nutritional risk with total costs of hospital care, length ...
