"Äijälä, Ville K." - Selaus tekijän mukaan TUNICRIS-julkaisut

Viitteet 1-6 / 6

    • Associations of mucinous differentiation and mucin expression with immune cell infiltration and prognosis in colorectal adenocarcinoma: Molecular Diagnostics 

      Elomaa, Hanna; Tarkiainen, Vilma; Äijälä, Ville K.; Sirniö, Päivi; Ahtiainen, Maarit; Sirkiä, Onni; Karjalainen, Henna; Kastinen, Meeri; Tapiainen, Vilja V.; Rintala, Jukka; Meriläinen, Sanna; Saarnio, Juha; Rautio, Tero; Tuomisto, Anne; Helminen, Olli; Wirta, Erkki Ville; Seppälä, Toni T.; Böhm, Jan; Mäkinen, Markus J.; Mecklin, Jukka Pekka; Väyrynen, Juha P. (2025)
      article
      <p>Background: The production of extracellular mucus and expression of mucins are commonly aberrant in colorectal cancer, yet their roles in tumour progression remain unclear. Methods: To investigate the potential ...

    • CDX2 and SATB2 loss are associated with myeloid cell infiltration and poor survival in colorectal cancer 

      Sirniö, Päivi; Elomaa, Hanna; Tuomisto, Anne; Äijälä, Ville K.; Karjalainen, Henna; Kastinen, Meeri; Tapiainen, Vilja V.; Sirkiä, Onni; Ahtiainen, Maarit; Helminen, Olli; Wirta, Erkki Ville; Rintala, Jukka; Meriläinen, Sanna; Saarnio, Juha; Rautio, Tero; Seppälä, Toni T.; Böhm, Jan; Mecklin, Jukka Pekka; Mäkinen, Markus J.; Väyrynen, Juha P. (02 / 2025)
      article
      <p>Background: Caudal-type homeobox 2 (CDX2) and special AT-rich sequence-binding protein 2 (SATB2) are transcription factors playing important roles in intestinal homeostasis and participating in the regulation of ...

    • Comprehensive characterization of micropapillary colorectal adenocarcinoma 

      Äijälä, Ville K.; Härkönen, Jouni; Mantere, Tuomo; Elomaa, Hanna; Sirniö, Päivi; Pohjanen, Vesa Matti; Sirkiä, Onni; Karjalainen, Henna; Kastinen, Meeri; Tapiainen, Vilja V.; Väyrynen, Sara A.; Pölönen, Petri; Ahtiainen, Maarit; Helminen, Olli; Wirta, Erkki Ville; Rintala, Jukka; Meriläinen, Sanna; Saarnio, Juha; Rautio, Tero; Pylkäs, Katri; Seppälä, Toni T.; Böhm, Jan; Mecklin, Jukka Pekka; Tuomisto, Anne; Mäkinen, Markus J.; Väyrynen, Juha P. (2025)
      article
      <p>Micropapillary colorectal adenocarcinoma is a morphologic subtype of colorectal cancer (CRC) with insufficiently characterized prognostic significance and biological features. We analyzed the histopathological, ...

    • Establishing Criteria for Tumor Necrosis as Prognostic Indicator in Colorectal Cancer 

      Kastinen, Meeri; Sirniö, Päivi; Elomaa, Hanna; Äijälä, Ville K.; Karjalainen, Henna; Tapiainen, Vilja V.; Pohjanen, Vesa Matti; Kemppainen, Janette; Sliashynskaya, Katja; Ahtiainen, Maarit; Rintala, Jukka; Meriläinen, Sanna; Rautio, Tero; Saarnio, Juha; Mattila, Taneli T.; Lindgren, Outi; Wirta, Erkki Ville; Helminen, Olli; Seppälä, Toni T.; Böhm, Jan; Mecklin, Jukka Pekka; Tuomisto, Anne; Mäkinen, Markus J.; Väyrynen, Juha P. (10 / 2024)
      article
      <p>Tumor necrosis has been reported to represent an independent prognostic factor in colorectal cancer, but its evaluation methods have not been described in sufficient detail to introduce tumor necrosis evaluation ...

    • Significance of mucin-suspended tumor bud-like structures in colorectal cancer 

      Äijälä, Ville K.; Sirniö, Päivi; Elomaa, Hanna; Karjalainen, Henna; Kastinen, Meeri; Tapiainen, Vilja V.; Ahtiainen, Maarit; Helminen, Olli; Wirta, Erkki Ville; Rintala, Jukka; Meriläinen, Sanna; Saarnio, Juha; Rautio, Tero; Seppälä, Toni T.; Böhm, Jan; Mecklin, Jukka Pekka; Tuomisto, Anne; Mäkinen, Markus J.; Väyrynen, Juha P. (04 / 2025)
      article
      Tumor budding (TB) is an independent predictor of adverse prognosis in colorectal cancer (CRC), defined as clusters of fewer than 5 tumor cells at the invasive margin of cancer. According to the international consensus ...

    • Stroma AReactive Invasion Front Areas (SARIFA), tumour immune microenvironment, and survival in colorectal cancer 

      Tapiainen, Vilja V.; Sirniö, Päivi; Elomaa, Hanna; Karjalainen, Henna; Äijälä, Ville K.; Kastinen, Meeri; Kehusmaa, Akseli; Pohjanen, Vesa Matti; Lindgren, Outi; Sirkiä, Onni; Ahtiainen, Maarit; Helminen, Olli; Wirta, Erkki Ville; Rintala, Jukka; Saarnio, Juha; Rautio, Tero; Seppälä, Toni T.; Böhm, Jan; Mecklin, Jukka Pekka; Tuomisto, Anne; Mäkinen, Markus J.; Väyrynen, Juha P. (2025)
      article
      Background: SARIFA (Stroma AReactive Invasion Front Areas), defined as the direct contact between a tumour cell cluster and adipose cells at the invasion margin, has been proposed as a prognostic marker in gastrointestinal ...