"Äijälä, Ville K" - Selaus tekijän mukaan TUNICRIS-julkaisut

Viitteet 1-4 / 4

    • Characteristics and significance of γδ T cells in colorectal cancer 

      Karjalainen, Henna; Härkönen, Jouni; Sirniö, Päivi; Elomaa, Hanna; Äijälä, Ville K; Kastinen, Meeri; Tapiainen, Vilja V; Väyrynen, Sara A; Ahtiainen, Maarit; Helminen, Olli; Wirta, Erkki-Ville; Rintala, Jukka; Meriläinen, Sanna; Saarnio, Juha; Rautio, Tero; Seppälä, Toni T; Böhm, Jan; Mecklin, Jukka-Pekka; Tuomisto, Anne; Mäkinen, Markus J; Väyrynen, Juha P (2025)
      article
      Gamma-delta T cells are a subset of T cells that have features of both innate and adaptive immunity. Their role in cancer remains controversial, since both anti- and protumor functions have been reported. We aimed to shed ...

    • Integrating tumor intraepithelial CD8+ and stromal FOXP3+ T cell densities as an enhanced immune prognostic index in colorectal cancer 

      Tuomisto, Anne; Sirniö, Päivi; Elomaa, Hanna; Karjalainen, Henna; Äijälä, Ville K; Kastinen, Meeri; Tapiainen, Vilja V; Ahtiainen, Maarit; Helminen, Olli; Wirta, Erkki-Ville; Rintala, Jukka; Meriläinen, Sanna; Saarnio, Juha; Rautio, Tero; Seppälä, Toni T; Böhm, Jan; Mecklin, Jukka-Pekka; Mäkinen, Markus J; Väyrynen, Juha P (2025)
      article
      High immune cell infiltration is generally associated with better survival in colorectal cancer (CRC). Recently, a prognostic score called CD8IE-FOXP3IS, which integrates the densities of tumor intraepithelial CD8+ and ...

    • Multimarker Assessment of B-Cell and Plasma Cell Subsets and Their Prognostic Role in the Colorectal Cancer Microenvironment 

      Sirkiä, Onni; Karjalainen, Henna; Elomaa, Hanna; Väyrynen, Sara A; Tuomisto, Anne; Sirniö, Päivi; Äijälä, Ville K; Tapiainen, Vilja V; Kastinen, Meeri; Wirta, Erkki-Ville; Helminen, Olli; Meriläinen, Sanna; Rintala, Jukka; Saarnio, Juha; Rautio, Tero; Seppälä, Toni T; Mäkinen, Markus J; Mecklin, Jukka-Pekka; Böhm, Jan; Ahtiainen, Maarit; Väyrynen, Juha P (2025)
      article
      PURPOSE: While the association between cytotoxic T lymphocytes and favorable prognosis in colorectal cancer is well established, the prognostic significance of B lymphocytes remain more ambiguous. This study aimed to assess ...

    • Significance of Th1 and Th2 Cell Densities and Th1/Th2 Cytokine Profiles in Colorectal Cancer 

      Ojanperä, Aino; Sirniö, Päivi; Elomaa, Hanna; Äijälä, Ville K; Karjalainen, Henna; Tapiainen, Vilja V; Kastinen, Meeri; Kehusmaa, Akseli; Rahkola, Oskari; Pohjanen, Vesa-Matti; Ahtiainen, Maarit; Helminen, Olli; Wirta, Erkki-Ville; Rintala, Jukka; Meriläinen, Sanna; Aro, Raila; Häivälä, Reetta; Saarnio, Juha; Rautio, Tero; Seppälä, Toni T; Böhm, Jan; Mecklin, Jukka-Pekka; Tuomisto, Anne; Mäkinen, Markus J; Väyrynen, Juha P (2025)
      article
      BACKGROUND: T-cell densities are associated with colorectal cancer outcome, but the significance of specific Th cell subsets is incompletely understood. We aimed to investigate the role of Th1 and Th2 cells and associated ...