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Viitteet 18366-18385 / 24990
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Protein supplementation versus standard feeds in underweight critically ill children: A pilot dual-centre randomised controlled trial protocol
(04.01.2022)
article<p>Introduction Protein-energy malnutrition, increased catabolism and inadequate nutritional support leads to loss of lean body mass with muscle wasting and delayed recovery in critical illness. However, there remains ... -
Protein-extending ACTN2 frameshift variants cause variable myopathy phenotypes by protein aggregation
(2024)
articleObjective: The objective of the study is to characterize the pathomechanisms underlying actininopathies. Distal myopathies are a group of rare, inherited muscular disorders characterized by progressive loss of muscle fibers ... -
Proteome-transcriptome alignment of molecular portraits achieved by self-contained gene set analysis: Consensus colon cancer subtypes case study
(2019)
article<p>Gene set analysis (GSA) has become the common methodology for analyzing transcriptomics data. However, self-contained GSA techniques are rarely, if ever, used for proteomics data analysis. Here we present a ... -
Proteomic characterization of primary and metastatic prostate cancer reveals reduced proteinase activity in aggressive tumors
(2021)
article<p>Prostate cancer (PCa) is a heterogeneous group of tumors with variable clinical courses. In order to improve patient outcomes, it is critical to clinically separate aggressive PCa (AG) from non-aggressive PCa ... -
Proteomics Analysis of R-Ras Deficiency in Oxygen Induced Retinopathy
(04 / 2023)
article<p>Small GTPase R-Ras regulates vascular permeability in angiogenesis. In the eye, abnormal angiogenesis and hyperpermeability are the leading causes of vision loss in several ischemic retinal diseases such as ... -
Proteomics of Deep Cervical Lymph Nodes after Experimental Traumatic Brain Injury
(05 / 2023)
article<p>Traumatic brain injury (TBI) damages the glymphatic-lymphatic system. We hypothesized that brain injury associated with trauma results in the enrichment of brain-relevant proteins in deep cervical lymph nodes ... -
Protocol for a double-blinded randomised controlled trial investigating the use of adjunct bicarbonate in carpal tunnel release: a single-centre study
(18.09.2023)
articleIntroduction This study aims to compare the effectiveness of buffered and non-buffered long-acting local anaesthetics in pain relief during and after carpal tunnel release (CTR) surgery. Carpal tunnel syndrome (CTS) is the ... -
A protocol for a proof-of-concept randomized control trial testing increased protein quantity and quality in ready-to-use therapeutic food in improving linear growth among 6-23-month-old children with severe wasting in Malawi
(08 / 2023)
article<p>Introduction Ready-to-use therapeutic foods (RUTFs) have successfully promoted recovery from severe wasting and increased treatment coverage. However, RUTFs do not sufficiently improve linear growth, leaving many ... -
Protocol for Controlled Desaturation Tests for Non-Invasive Pulse Oximeter Performance Testing
Computing in Cardiology (2024)
conferenceTo prove that the investigational pulse oximeter device is accurate also on low oxygen saturation levels, the testing must be done on human beings since there are no reference materials to ensure correct operation. The ISO ... -
Protocol for culturing olfactory epithelium organoids supporting neuronal differentiation
(19.12.2025)
articleThe olfactory epithelium (OE) contains stem cells capable of generating olfactory sensory neurons throughout life, making it a valuable model for studying epithelial neurogenesis. We present a protocol to develop a highly ... -
Protocol of a randomised, controlled trial comparing immediate curative therapy with conservative treatment in men aged ≥75 years with non-metastatic high-risk prostate cancer (SPCG 19/GRand-P)
(06 / 2024)
articleBackground: Older men (aged ≥75 years) with high risk, non-metastatic prostate cancer (PCa) are increasingly treated with curative therapy (surgery or radiotherapy). However, it is unclear if curative therapy prolongs life ... -
Protocol: A randomized controlled trial to assess effectiveness of a 12-month lifestyle intervention to reduce cardiovascular disease risk in families ten years after pre-eclampsia (FINNCARE)
(04 / 2022)
article<p>Pre-eclampsia (PE) is a multisystem progressive disorder affecting 3–5% of pregnancies. PE independently increases the risk for premature cardiovascular disease (CVD) in mothers and their children long-term. The ... -
Protonation-induced fluorescence modulation of carbazole-based emitters
(07.02.2022)
articleThe development of purely organic fluorescence emitters is of great importance for their low cost and high performance. Responding to this demand, carbazole is a promising emitter due to its extensive freedom for ... -
Prototype design and experimental evaluation of autonomous collaborative communication system for emerging maritime use cases
(03.06.2021)
article<p>Automated systems have been seamlessly integrated into several industries as part of their industrial automation processes. Employing automated systems, such as autonomous vehicles, allows industries to increase ... -
Prototype master protocol for benchmarking of real-world follow-up data in glaucoma
(2025)
articlePurpose: The purpose of this study was to create a prototype master protocol for benchmarking glaucoma real-world data (RWD). Benchmarking is part of the digital innovation strategy of the Finnish aces-rwm ecosystem ... -
A Prototype of an RFID-Based Command Sleeve with Changeable Microcircuits
(2024)
conferenceThis this study presents the initial prototype of a command sleeve designed to assist in pre-determined daily tasks and communication of those who have co-morbidities in terms of both speech and motor skills. The command ... -
A prototype protocol for evaluating the real-world data set using a structured electronic health record in glaucoma
(03 / 2023)
articlePurpose: As the first step in monitoring and evaluating day-to-day glaucoma care, this study reports all real-world data recorded during the first full year after the implementation of a prototype for glaucoma-specific ... -
The prototypical Narrative Elements in Information Systems Implementation Narratives: Towards Critical Narrative Approach.
European Conference on Information Systems (2022)
conferenceInformation systems (IS) implementations, e.g., their development and use, emerges from subjectively perceived social realities. Practitioners such as developers, managers, and users, make sense of the world essentially ...
