Haku
Viitteet 1-7 / 7
Small-molecules as regulatory T cell modulators: A pilot screen
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Backround and aims: Regulatory T cells are widely recognized as key players of immune control and have been shown to function in many immune related diseases. This has lead to intensive research efforts and high hopes for ...
Characterization of repression capability of Sin3-associated protein 30-like and its alternatively spliced isoforms
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and Aims: Within the nucleus of eukaryotic cell, DNA is packaged with histone proteins to from nucleosomes that arrange further to form higher-order packaged structures. This three dimensional structure forms a ...
Hyperuricemia and the renin-angiotensin-aldosterone system in experimental renal insufficiency
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and Aims – Hyperuricemia is associated with renal insufficiency and may predispose to Na+ retention and hypertension. Whether hyperuricemia plays a causal role in the pathogenesis of cardiovascular disease remains ...
Neural stem cell transplantation in mouse model of juvenile neuronal ceroid-lipofuscinosis
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and Aims: This thesis investigates the suitability of neural stem cell transplantation in a mouse model of juvenile neuronal ceroid-lipofuscinosis (JNCL). JNCL is a childhood neurodegenerative disease leading ...
Brain Phenotype of Car9-/- Knock-out Mouse
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Carbonic anhydrase IX (CA IX) is a membrane-bound isozyme, which shows only low expression in the normal human brain. Previously Car9-/- knock-out mice have been stated to be aggressive and hyperactive ...
Identification of novel osteogenic compounds that act synergistically with BMP-2
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: In reconstructive surgery, repair of bone defects is a major reparative problem. Bone morphogenetic proteins (BMPs) have shown significant potential in bone formation, however, there are many inherent ...
Clustering of Gene Ontologies in Genomes
(2008)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tutkimuksen tausta ja tavoitteet:
Proteiineja koodaavat geenit eivät ole satunnaisesti jakautuneina kromosomeihin, vaikkakin ne edustavat vain pientä osaa genomista. Geenien klusteroitumisesta on saatu viitteitä usealla ...