Haku
Viitteet 61-67 / 67
Bioinformatic analysis of next-generation sequencing data
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Backround and aims:In a recent linkage study involving 69 Finnish HPC (Hereditary prostate cancer) families, a novel prostate cancer susceptibility locus 2q37.3 was found (Cropp et al. 2011). In addition a signal from ...
Validation of susceptibility locus 2q37.3 mutations in prostate cancer
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Prostate cancer is the most commonly diagnosed cancer in men in Finland and other industrialized countries. The causes of prostate cancer are still relatively poorly known, but family history is one ...
Identification of novel interacting proteins for proprotein convertase furin in T cells
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Proprotein convertase furin cleaves inactive proproteins into their biologically active forms and regulates the bioavailability of many cellular proteins. Recently, furin was connected to immunology ...
IMPROVED PHAGE DISPLAY METHODS FOR THE SELECTION OF DNA-SHUFFLED AVIDIN MUTANTS
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tutkielman tausta ja tavoitteet: Faagiseulonta on proteiinikirjastojen seulonnassa käytetty menetelmä, jonka avulla proteiineja ja peptidejä voidaan valikoida niiden ligandinsitomiskyvyn tai muiden biokemiallisten ...
Concordance between Pathway Databases and Refinement of Pathways for Computational Analysis
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Tutkimuksen tausta ja tavoitteet: Biologiassa tutkimus suuntautuu kokoajan kohti systeemitason tutkimusta. Enää ei tutkita vain yhtä tai muutamaa geeniä, vaan keskitytään kokonaisuuteen, jossa ne esiintyvät. Signalointireitit ...
Applying genome-wide approach to define the genetics of low-density lipoprotein oxidation in two large cohorts
(2013)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background: Cardiovascular diseases (CVD) are the number one killer and cause of disability in today’s world. Oxidized low-density lipoprotein (oxLDL) is considered to be a key factor in the development of atherosclerosis ...