Haku
Viitteet 31-40 / 58
Defining the mechanism of action of multi-walled carbon nanotubes on immune cells in vitro
(2019)
Pro gradu -tutkielma
Pro gradu -tutkielma
Engineered nanomaterials (ENM) are a rapidly expanding class of chemicals with applications spanning from cosmetics to food, and from industrial applications to pharmaceuticals. Some ENM are already known to be harmful to ...
Investigating coeliac disease patient transglutaminase 2-specific B cells in the duodenal bulb
(2019)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Coeliac disease (CD) is a gluten-induced disorder, which is characterized by an autoimmune response against enzyme transglutaminase 2 (TG2). In CD, TG2-specific plasma cells secrete immunoglobulin (Ig) ...
Biochemical and biophysical characterization of saliva- and milk human carbonic anhydrase VI : maidon ja syljen hiilihappoanhydraasi VI:n biokemiallinen ja biofysikaalinen karakterisointi
(2019)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims of study: Carbonic anhydrase VI, CA VI, belongs to carbonic anhydrase isoenzymes that is known to secrete from serous acinar cells in the salivary glands and mammary gland to saliva and milk, respectively. ...
Targeting QTLs using the CRISPR/Cas9 system in yeast
(2017)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and objectives: There is still limited knowledge about how phenotypes arise from genetic loci. It is especially difficult to understand complex traits that are affected by several both genetic and environmental ...
Production, purification and characterization of Coxsackievirus B1 virus-like particles
(2017)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Virus-like particles (VLPs) are promising vaccine candidates, usually eliciting broad and strong immune responses in humans. The aim of this study was to produce VLPs for coxsackievirus B1 (CVB1). CVB ...
Establishment and characterisation of new human induced pluripotent stem cell lines and cardiomyocyte differentiation : a comparative view
(2017)
Pro gradu -tutkielma
Pro gradu -tutkielma
Research background and aims. The aim of this study was to establish and characterise iPSC-lines generated with two different methods, as well as to differentiate the created cells into cardiomyocytes, maintaining a ...
Development of MP-SPR biosensor analysis methology
(2017)
Pro gradu -tutkielma
Pro gradu -tutkielma
Optical biosensors have gained high regard in the field of drug industry and clinical diagnostics owing to the high specificity of biological recognition elements as well as to the non-invasiveness of optical detection ...
Neuronal differentiation, maturation and adhesion in vitro in 3D - effect of cell source and hydrogel scaffold
(2018)
Pro gradu -tutkielma
Pro gradu -tutkielma
There is a great need for novel tissue engineering (TE) applications for central nervous system (CNS) defects, like spinal cord injury (SCI). One promising approach for neural TE is to combine human stem cell-derived neural ...
OXGR1 overexpression as putative prostate cancer promoting factor
(2017)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Prostate cancer is the most common cancer diagnosed in men. While it often has indolent course, and diagnosed men more commonly perish to comorbidities, it remains the third-leading cause of cancer ...
Phylogenetic analysis and database of putative bacterial avidins
(2017)
Pro gradu -tutkielma
Pro gradu -tutkielma
Since the discovery of the first avidin in the chicken (Gallus gallus) egg-white in the 1940s, avidins have been identified in all avians, amphibians, reptiles, fish, some non-chordate, two fungi, and several bacteria. ...