Haku
Viitteet 31-34 / 34
Analysis of nucleotide repeats at variation sites
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Abstract
Background and aims:Nucleotide repeats are sequences that are repeated two or more times in the genome. They are generally classified into two broad groups as tandem repeats or dispersed repeats. They can be found ...
Genome-Wide Comparison of Copy Number Variations in Finnish Familial Prostate and Breast Cancers
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Abstract
Background and aims: Prostate and breast cancers are the most prevalent types of cancer in all Western countries including Finland. For both cancer types, there is a “missing heritability” - the genetic defects ...
Bioinformatic analysis of next-generation sequencing data
(2012)
Pro gradu -tutkielma
Pro gradu -tutkielma
Backround and aims:In a recent linkage study involving 69 Finnish HPC (Hereditary prostate cancer) families, a novel prostate cancer susceptibility locus 2q37.3 was found (Cropp et al. 2011). In addition a signal from ...
Applying genome-wide approach to define the genetics of low-density lipoprotein oxidation in two large cohorts
(2013)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background: Cardiovascular diseases (CVD) are the number one killer and cause of disability in today’s world. Oxidized low-density lipoprotein (oxLDL) is considered to be a key factor in the development of atherosclerosis ...