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Improving performance of a microfluidic immunoassay using a finite element method modeling
(2013)
Diplomityö
Diplomityö
In-vitro diagnostics is currently going through changes. Instead of using central laboratories to analyze samples, point-of-care (POC) diagnostic devices are used more and more. With these devices tests can be performed ...
Fabrication and characterization of collagen, hyaluronic acid and chondroitin sulfate scaffolds for cartilage tissue engineering applications
(2015)
Diplomityö
Diplomityö
Native cartilage has very little capacity for self-healing and even the current clinical methods have limited ability to regenerate functional cartilage. In the recent decade research related to cartilage repair has been ...
Nitrogen removal from mining wastewaters in bioreactors
(2013)
Diplomityö
Diplomityö
One of the main challenges in the mining industry is the emission of harmful components to the environment. Explosive residues and cyanide-containing leaching solutions release ammonium and nitrate to the environment, which ...
A rapid cell culture protocol for screening material cytocompatibility
(2016)
Diplomityö
Diplomityö
Hydrogels differ from many other cell culture substrates in that they provide a three-dimensional, soft environment for cells, opposed to a two-dimensional surface on which cells are traditionally cultured. This geometry ...
Colloidal Gold and Paramagnetic Labels in Lateral Flow Assay Detecting Ricin
(2012)
Diplomityö
Diplomityö
Lateral flow assay is an antibody-based, fast, easy to use, affordable and accurate measurement method for the detection of small quantities of substances. The analytes are detected with antibody-label complex and the label ...
Advanced Methods for Culturing Neuronal Cells with Microstructures
(2011)
Diplomityö
Diplomityö
During the development of the neural tissue of the nervous system, supporting neuroglial cells and the extracellular matrix (ECM) guide the migration of the immature functional neurons, provide them with a scaffold to grow ...
Dynamics of Stochastic Sequence-Level Models of Transcription and Translation in Prokaryotes
(2011)
Diplomityö
Diplomityö
In prokaryotes, transcription and translation are dynamically coupled, as the latter starts before the former is completed. Also, from one transcript, several translation events occur in parallel. To study how events in ...
Numerical evaluation of Specific Absorption Rate with two realistic mobile phone models
(2015)
Diplomityö
Diplomityö
This thesis is a numerical evaluation of SAR compliance assessment with realistic exposure conditions using accurate human and mobile phone models. Four hand models with four adult and five child head models were simulated ...
The role of a putative tumor suppressor migration and invasion inhibitory protein in prostate cancer
(2015)
Diplomityö
Diplomityö
Prostate cancer is the most common cancer in Western countries. As the disease proceeds to castration resistant phase, it often leads to death due to lack of effective treatment methods and lack of knowledge of molecular ...
Hydrogels for 3D Culture of Human Corneal Cells Aiming for Tissue Engineered Corneal Application
(2016)
Diplomityö
Diplomityö
The cornea is a transparent tissue protecting the most anterior part of the eye and if it is damaged, it may result in a partial or complete loss of vision. Millions of patients are in need of donor cornea, but there is a ...