Haku
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Redox dyes in the detection of mycobacterial viability
(2021)
Pro gradu -tutkielma
Pro gradu -tutkielma
In this master’s thesis, I optimize the conditions of use of redox dyes to detect the viability of mycobacteria. Mycobacterium tuberculosis causes tuberculosis that infects millions of people every year. In 2019, 1.4 million ...
Antigen-antibody affinity mapping: Characterization of monoclonal antibodies reactivity to viral proteins
(2021)
Diplomityö
Diplomityö
Enteroviruses (EVs) belong to the Picornaviridae family, and their genomes are made up of single-stranded, positive-sense RNA. Infections from EVs can be asymptomatic or have a wide variety of symptoms, including paralysis, ...
Calcium Activation of Oocytes for Poor Prognosis Infertility Patients
(2021)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background & aims: Intracytoplasmic sperm injection (ICSI) is one of the most significant techniques in in vitro fertilization (IVF), especially for male factor infertility. Various studies have shown that couples may ...
New insights into Ror1, Ror2, and Ptk7 mediated Wnt signaling
(2021)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Wnt signaling has central role during embryonic development and adult tissue homeostasis. Dysregulation of this important signaling can lead to different developmental disorders and other diseases such ...
Modeling Single Cell Properties from Histological Images
(2021)
Pro gradu -tutkielma
Pro gradu -tutkielma
In modern pathology, digitized images of histological sections are routinely used in defining phenotypes and characteristics for different areas of the tissue. Digital images are created from stained histological slides ...
SARS-CoV-2 virus in Finnish wastewater: Optimization of RT-ddPCR method and comparison with the RT-qPCR method in virus detection
(2021)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: SARS-CoV-2 is a single-stranded envelope RNA virus that causes currently occurring COVID-19 pandemic. Those infected with the virus excrete it in wastewater through urine, feces, saliva and various ...
Characterization of Wnt5a-ROR Pathway in Cisplatin-resistant Ovarian Cancer Cell Lines
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Epithelial ovarian cancers (OC), of which 70–80% are high-grade serous ovarian cancer (HGSOC), are the leading cause of gynecological cancer deaths in developed countries. Currently, the standard OC ...
Fabrication of Fibrin Fibres to Guide Cellular Alignment
(2021)
Diplomityö
Diplomityö
Many tissues have a distinctly aligned microstructure which is critical for their optimal function such as muscle tissue and vasculature. Therefore, in order to regenerate or model those tissues, tissue engineering constructs ...