Haku
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The association of claudin-19 with human embryonic stem cell-derived retinal pigment epithelium primary cilia
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: Claudin-19 is the most abundant claudin protein in human retinal pigment epithelia. There have been only few observations of ciliary localization of claudin-19, and its role in developmentally important ...
The Functional Consequences of ZNF414 Overexpression in Pancreatic Cancer Cells
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: All cancers are known to arise from genetic mutations in specific driver genes, including oncogenes, tumor suppressor genes and DNA repair genes. DNA alterations in these genes lead to malfunction of ...
Integrative analysis of multi-genomics using variable selection for autism data
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
The role of proprotein convertase FURIN in the activation of N-glycosyltransferase Gnt-V
(2020)
Pro gradu -tutkielma
Pro gradu -tutkielma
Background and aims: PCSKs are an important enzyme family in protein maturation and needed for several biological processes. Another, equally important enzyme family, N-glycosyltransferase Gnt, also affects many aspects ...