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A System for Intraoperative Cancer Margin Detection by Diathermy Smoke Analysis
(2017)
Diplomityö
Diplomityö
In this thesis, a method and system capable of intraoperative cancer margin detection, with potential to improve the current methodology, is introduced, tested and validated. The system is based on diathermy smoke analysis ...
Lääkeaineiden kulkeutuminen ja poistuminen urbaanin hydrologisen kierron aikana
(2017)
Diplomityö
Diplomityö
Tässä työssä tavoitteena oli selvittää lääkeaineiden esiintyminen ja poistuminen urbaanin hydrologisen kierron aikana todellisessa pienen mittakaavan ympäristössä. Lääkeaineiden tutkimus jätevesissä ja ympäristössä on ...
Reliability and Limitations of Compression Testing of Various Biomaterials
(2017)
Diplomityö
Diplomityö
Tissue-engineered scaffolds should mimic, as closely as possible, the one of the tissues to be replaced. Hence, mechanical tests are of paramount importance. However, as there are various biomaterials, with distinct ...
Porous poly(butylene succinate) films as promising candidates for retinal tissue engineering
(2018)
Diplomityö
Diplomityö
In the developed world, degenerative retinal diseases such as age-related macular degeneration (AMD) are the leading cause of senior citizens’ vision loss. AMD is caused by the degeneration of the retinal pigment epithelium ...
Adhesion Ligand-Presenting Hydrogels for Studying Stem Cell Behaviours in Three Dimensions
(2017)
Diplomityö
Diplomityö
In their natural microenvironment, stem cells are surrounded by various mechanical and biochemical signals, and growing evidence suggests that, similarly to the biochemical cues, the biophysical properties of the ...
Inhibition of fibroblast growth factor receptor in FGFR3:TACC3 fusion positive glioblastoma cells
(2017)
Diplomityö
Diplomityö
Glioblastoma multiforme is the most common of adult primary brain tumors. It is a highly aggressive form of diffuse gliomas and with current treatments median life expectancy of patients with glioblastoma is approximately ...
The Effects of Inhibiting Mechanotransductive Cell Signaling Pathways in Human Bone Marrow Stromal Cells in 2D vs. 3D Culture
(2017)
Diplomityö
Diplomityö
Mechanotransduction is the process of mechanical information transfer between a cell and its surroundings into biochemical responses. Involved in mechanotransduction are several components: extracellular matrix (ECM), ...
A screen for biofilm mutant Mycobacterium marinum
(2017)
Diplomityö
Diplomityö
Mycobacterium tuberculosis infects millions of people every year and in 2015 1.8 million people died from the disease. The main problem is that M. tuberculosis has a natural resistance to many antibiotics. Studying of M. ...
Recombinant whole cell bacterial biosensors in the screening of natural extracts
(2018)
Diplomityö
Diplomityö
Natural extracts have been used in traditional medicine as remedies to treat for example inflammations. During the era of modern medicine, there has been a shift towards usage of synthetic substances. However, many bacteria ...
Up-Scaling of Microbial Co-Cultures
(2018)
Diplomityö
Diplomityö
Microbial fermentations are used to produce pharmaceuticals, chemicals, and fuels. Side product formation along with considerable losses in productivities and yields are often encountered in transition from laboratory- to ...