Haku

Influenza A is a highly contagious respiratory virus whose surface protein hemagglutinin (HA) constantly obtains mutations at its five antigenic sites. These mutations occasionally lead to acquisition of new N-linked ...

Background and aims: Millions of people die every year of intestinal parasite diseases. Two epidemiologically important parasites, Giardia lamblia and Cryptosporidium species (spp.) cause e.g. diarrhoea, vomiting and at ...

Bruton tyrosine kinase (BTK) belong to the Tec family of non receptor tyrosine kinases that is a predominant cytoplasmic protein found in cells of humans that is responsible for B-lymphocyte development, differentiation, ...

Recently, a significant number of studies regarding the activation mechanism of talin's vinculin binding site (VBS) have been published. Since the hydrophobic VBS is in natural talin buried inside the helix structure, a ...

Background and aims: Prostate cancer is a common malignancy affecting millions of men worldwide. The molecular mechanisms involved in prostate cancer are poorly understood. Genomic copy-number alterations are common in ...

Background and aim: The role of bone morphogenetic proteins (BMP) 4 and 7 in primary breast cancer is peculiar as they are known to induce cell proliferation in some tumor cells and also to reduce tumor growth in some ...

*Background and aims:* Defects in mitochondrial respiratory chain produce diseases commonly referred as mitochondrial diseases. Mitochondrial diseases most often affect tissues that have high energy demands, particularly ...